Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases.
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The Epithelial Sodium Channel and the Processes of Wound HealingEpithelial Sodium and Chloride Channels and AsthmaEarly pulmonary inflammation and lung damage in children with cystic fibrosisMolecular basis for pH-dependent mucosal dehydration in cystic fibrosis airwaysAirway hydration and COPDIon transporting proteins of human bronchial epitheliumBactericidal/Permeability-increasing protein fold-containing family member A1 in airway host protection and respiratory diseaseSPLUNC1 expression reduces surface levels of the epithelial sodium channel (ENaC) in Xenopus laevis oocytes.Structural characterization of the pulmonary innate immune protein SPLUNC1 and identification of lipid ligands.FRET-based and other fluorescent proteinase probes.Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung.SPLUNC1 Is a Significant Marker in Pleural Effusion from Lung Cancer Compared to Tuberculosis.Energetic and structural basis for activation of the epithelial sodium channel by matriptasePertussis toxin exacerbates and prolongs airway inflammatory responses during Bordetella pertussis infection.Glandular Proteome Identifies Antiprotease Cystatin C as a Critical Modulator of Airway Hydration and Clearance.AP301, a synthetic peptide mimicking the lectin-like domain of TNF, enhances amiloride-sensitive Na(+) current in primary dog, pig and rat alveolar type II cells.Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion.Structural Features Essential to the Antimicrobial Functions of Human SPLUNC1.Reduced sodium transport with nasal administration of the prostasin inhibitor camostat in subjects with cystic fibrosis.Short palate, lung, and nasal epithelial clone-1 is a tightly regulated airway sensor in innate and adaptive immunity.Mechanism of action of novel lung edema therapeutic AP301 by activation of the epithelial sodium channel.Proteases, cystic fibrosis and the epithelial sodium channel (ENaC).Does epithelial sodium channel hyperactivity contribute to cystic fibrosis lung disease?Mammalian short palate lung and nasal epithelial clone 1 (SPLUNC1) in pH-dependent airway hydrationMicroRNA-200b regulates distal airway development by maintaining epithelial integrity.Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets.SPX-101 is a Novel ENaC-targeted Therapeutic for Cystic Fibrosis that Restores Mucus Transport.δβγ-ENaC is inhibited by CFTR but stimulated by cAMP in Xenopus laevis oocytes.Epithelial sodium channel silencing as a strategy to correct the airway surface fluid deficit in cystic fibrosis.A Protease Inhibitor Tackles Epithelial Sodium Channels in Cystic Fibrosis.Cathepsin B contributes to Na+ hyperabsorption in cystic fibrosis airway epithelial cultures.Morpholino knockdown of the ubiquitously expressed transmembrane serine protease TMPRSS4a in zebrafish embryos exhibits severe defects in organogenesis and cell adhesion.Soluble mucus component CLCA1 modulates expression of leukotactic cytokines and BPIFA1 in murine alveolar macrophages but not in bone marrow-derived macrophages.Recent advances in developing therapeutics for cystic fibrosis
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Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 18 April 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Regulation of the epithelial N ...... id volume by serine proteases.
@en
Regulation of the epithelial N ...... id volume by serine proteases.
@nl
type
label
Regulation of the epithelial N ...... id volume by serine proteases.
@en
Regulation of the epithelial N ...... id volume by serine proteases.
@nl
prefLabel
Regulation of the epithelial N ...... id volume by serine proteases.
@en
Regulation of the epithelial N ...... id volume by serine proteases.
@nl
P2093
P2860
P1433
P1476
Regulation of the epithelial N ...... id volume by serine proteases.
@en
P2093
Erol A Gaillard
M Jackson Stutts
Martina Gentzsch
Pradeep Kota
Robert Tarran
P2860
P2888
P356
10.1007/S00424-010-0827-Z
P577
2010-04-18T00:00:00Z