Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants - Wikidata - awgldk - TriplyDB

Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants

Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants

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Constitutive Signaling by NOTCH1 HD Domain Mutants

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Q37753053-0B0186BF-E445-4BBA-92B2-DEC809B2633B

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Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants

http://www.wikidata.org/entity/Q37753074

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An instance of the biological ...... domain mutants in Homo sapiens

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biologisch proces

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Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants

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Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants

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prefLabel

Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants

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Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila.

Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1

Mind bomb-2 is an E3 ligase for Notch ligand

Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta

Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta

An obligatory role of mind bomb-1 in notch signaling of mammalian development

Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1.

The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta.

The interplay between DSL proteins and ubiquitin ligases in Notch signaling.

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reactome:R-HSA-2737728

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biological process

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Constitutive Signaling by NOTCH1 HD Domain Mutants

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R-HSA-2737728

http://www.w3.org/2001/XMLSchema#string

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DLL/JAG:NOTCH1 HD domain mutants

Ub-DLL/JAG:NOTCH1 HD domain mutants

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