about
P-TEFb goes viralHIV-1 buds predominantly at the plasma membrane of primary human macrophages.High natural permissivity of primary rabbit cells for HIV-1, with a virion infectivity defect in macrophages as the final replication barrier.HIV-susceptible transgenic rats allow rapid preclinical testing of antiviral compounds targeting virus entry or reverse transcriptionPrimary T-cells from human CD4/CCR5-transgenic rats support all early steps of HIV-1 replication including integration, but display impaired viral gene expression.Preparation, characterization, and safety evaluation of poly(lactide-co-glycolide) nanoparticles for protein delivery into macrophages.Pharmacovirological impact of an integrase inhibitor on human immunodeficiency virus type 1 cDNA species in vivoRestrictions to HIV-1 replication in resting CD4+ T lymphocytes.P-TEFb goes viral.Architecture and regulation of the HIV-1 assembly and holding compartment in macrophages.Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo.Monocytes and Macrophages as Viral Targets and Reservoirs
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2006
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Role of macrophages in HIV infection and persistence.
@en
Role of macrophages in HIV infection and persistence.
@nl
type
label
Role of macrophages in HIV infection and persistence.
@en
Role of macrophages in HIV infection and persistence.
@nl
prefLabel
Role of macrophages in HIV infection and persistence.
@en
Role of macrophages in HIV infection and persistence.
@nl
P2860
P356
P1476
Role of macrophages in HIV infection and persistence.
@en
P2093
Oliver T Keppler
Stephanie Venzke
P2860
P304
P356
10.1586/1744666X.2.4.613
P577
2006-07-01T00:00:00Z