Therapeutic applications of bioactive sphingolipids in hematological malignancies.
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Elisidepsin Interacts Directly with Glycosylceramides in the Plasma Membrane of Tumor Cells to Induce Necrotic Cell DeathInhibition of sphingosine kinase 2 downregulates the expression of c-Myc and Mcl-1 and induces apoptosis in multiple myeloma.Triangulated mal-signaling in Alzheimer's disease: roles of neurotoxic ceramides, ER stress, and insulin resistance reviewedSphingosine kinase 1 is a potential therapeutic target for nasopharyngeal carcinoma.Therapeutic potential of targeting ceramide/glucosylceramide pathway in cancer.Changes in molecular biology of chronic myeloid leukemia in tyrosine kinase inhibitor era.Microbubble-based enhancement of radiation effect: Role of cell membrane ceramide metabolism.Increased ceramide production sensitizes breast cancer cell response to chemotherapy.Bioactive lipids-based pH sensitive micelles for co-delivery of doxorubicin and ceramide to overcome multidrug resistance in leukemia.The combination of a sphingosine kinase 2 inhibitor (ABC294640) and a Bcl-2 inhibitor (ABT-199) displays synergistic anti-myeloma effects in myeloma cells without a t(11;14) translocation.Sphingosine but not sphingosine-1-phosphate stimulates suicidal erythrocyte death.Multiple Roles of Glycans in Hematological Malignancies
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Therapeutic applications of bioactive sphingolipids in hematological malignancies.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on October 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Therapeutic applications of bioactive sphingolipids in hematological malignancies.
@en
Therapeutic applications of bioactive sphingolipids in hematological malignancies.
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type
label
Therapeutic applications of bioactive sphingolipids in hematological malignancies.
@en
Therapeutic applications of bioactive sphingolipids in hematological malignancies.
@nl
prefLabel
Therapeutic applications of bioactive sphingolipids in hematological malignancies.
@en
Therapeutic applications of bioactive sphingolipids in hematological malignancies.
@nl
P2860
P356
P1476
Therapeutic applications of bioactive sphingolipids in hematological malignancies.
@en
P2093
Huseyin Atakan Ekiz
Yusuf Baran
P2860
P304
P356
10.1002/IJC.25478
P577
2010-10-01T00:00:00Z