The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution. - Wikidata - awgldk - TriplyDB

The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.

The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.

http://www.wikidata.org/entity/Q37760941

about

Influence of drug transporters and stereoselectivity on the brain penetration of pioglitazone as a potential medicine against Alzheimer's disease Expression and clinical significance of multidrug resistance proteins in brain tumors.Stereoselective Modulation of P-Glycoprotein by Chiral Small Molecules.Personalized prescribing: a new medical model for clinical implementation of psychotropic drugs.Stereoselectivity of chiral drug transport: a focus on enantiomer-transporter interaction.Overton's rule helps to estimate the penetration of anti-infectives into patients' cerebrospinal fluid Stereochemical considerations in pharmacokinetic processes of representative antineoplastic agents.Steady-state plasma concentration of donepezil enantiomers and its stereoselective metabolism and transport in vitro.

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The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.

http://www.wikidata.org/entity/Q37760941

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on August 2010

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.

@en

The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.

@nl

type

label

The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.

@en

The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.

@nl

prefLabel

The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.

@en

The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.

@nl

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17425251003789394

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Expert Opinion on Drug Metabolism & Toxicology

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The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution.

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Maria Dobrinas

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P2860

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

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Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

A "silent" polymorphism in the MDR1 gene changes substrate specificity

Increased drug delivery to the brain by P-glycoprotein inhibition.

P-Glycoprotein, a gatekeeper in the blood-brain barrier.

Expression and function of multidrug resistance transporters at the blood-brain barriers.

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs.

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.

Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence.

P304

953-965

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scholarly article

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10.1517/17425251003789394

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8

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6

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Pierre-Alain Carrupt

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2010-08-01T00:00:00Z

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20504109

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enantioselectivity