Major histocompatibility complex class I binding predictions as a tool in epitope discovery.
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Vaccines: from empirical development to rational designMultiple viral ligands naturally presented by different class I molecules in transporter antigen processing-deficient vaccinia virus-infected cellsBioinformatics for cancer immunology and immunotherapyHLA class I molecular variation and peptide-binding properties suggest a model of joint divergent asymmetric selection.NNAlign: a web-based prediction method allowing non-expert end-user discovery of sequence motifs in quantitative peptide dataSequence-based in silico analysis of well studied hepatitis C virus epitopes and their variants in other genotypes (particularly genotype 5a) against South African human leukocyte antigen backgroundsUse of "one-pot, mix-and-read" peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle.Whole-genome immunoinformatic analysis of F. tularensis: predicted CTL epitopes clustered in hotspots are prone to elicit a T-cell response.PeptX: using genetic algorithms to optimize peptides for MHC binding.State of the art and challenges in sequence based T-cell epitope predictionIn silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem-Cell Transplant Donors and Recipients: Understanding the Quantitative Immunobiology of Allogeneic TransplantationConditional ligands for Asian HLA variants facilitate the definition of CD8+ T-cell responses in acute and chronic viral diseases.T cell antigen discovery using soluble vaccinia proteome reveals recognition of antigens with both virion and nonvirion association.Efficacy of HLA-DRB1∗03:01 and H2E transgenic mouse strains to correlate pathogenic thyroglobulin epitopes for autoimmune thyroiditis.Key role of human leukocyte antigen in modulating human immunodeficiency virus progression: An overview of the possible applications.Identification of human leukemia antigen A*0201-restricted epitopes derived from epidermal growth factor pathway substrate number 8Predictions versus high-throughput experiments in T-cell epitope discovery: competition or synergy?West Nile virus T-cell ligand sequences shared with other flaviviruses: a multitude of variant sequences as potential altered peptide ligandsMHCcluster, a method for functional clustering of MHC moleculesTowards the knowledge-based design of universal influenza epitope ensemble vaccines.Improved pan-specific MHC class I peptide-binding predictions using a novel representation of the MHC-binding cleft environment.Prediction of epitopes using neural network based methods.Toward more accurate pan-specific MHC-peptide binding prediction: a review of current methods and tools.Census of cytosolic aminopeptidase activity reveals two novel cytosolic aminopeptidases.Novel approaches in polyepitope T-cell vaccine development against HIV-1.Design of Polyepitope DNA Vaccine against Breast Carcinoma Cells and Analysis of Its Expression in Dendritic Cells.Glucagon-reactive islet-infiltrating CD8 T cells in NOD mice.Neoepitopes as cancer immunotherapy targets: key challenges and opportunities.Prediction of peptide binding to a major histocompatibility complex class I molecule based on docking simulation.HLaffy: estimating peptide affinities for Class-1 HLA molecules by learning position-specific pair potentials.Modeling Sequence-Dependent Peptide Fluctuations in Immunologic Recognition.Identification and evaluation of the novel immunodominant antigen Rv2351c from Mycobacterium tuberculosis.MFPred: Rapid and accurate prediction of protein-peptide recognition multispecificity using self-consistent mean field theory.Role of individual's T-cell immunome in controlling HIV-1 progression.In silico peptide-binding predictions of passerine MHC class I reveal similarities across distantly related species, suggesting convergence on the level of protein function.Host genotype and time dependent antigen presentation of viral peptides: predictions from theory.Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes.NetMHCstab - predicting stability of peptide-MHC-I complexes; impacts for cytotoxic T lymphocyte epitope discovery.NetTepi: an integrated method for the prediction of T cell epitopes.Determining T-cell specificity to understand and treat disease
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Major histocompatibility complex class I binding predictions as a tool in epitope discovery.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 26 May 2010
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Major histocompatibility compl ...... s a tool in epitope discovery.
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Major histocompatibility compl ...... s a tool in epitope discovery.
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type
label
Major histocompatibility compl ...... s a tool in epitope discovery.
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Major histocompatibility compl ...... s a tool in epitope discovery.
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prefLabel
Major histocompatibility compl ...... s a tool in epitope discovery.
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Major histocompatibility compl ...... s a tool in epitope discovery.
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Major histocompatibility compl ...... as a tool in epitope discovery
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P2093
Claus Lundegaard
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P356
10.1111/J.1365-2567.2010.03300.X
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2010-05-26T00:00:00Z