Uniformly curated signaling pathways reveal tissue-specific cross-talks and support drug target discovery.
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Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewSignalogs: orthology-based identification of novel signaling pathway components in three metazoansLinking proteins to signaling pathways for experiment design and evaluationCellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms.Protein conservation and variation suggest mechanisms of cell type-specific modulation of signaling pathways.Integrating protein-protein interaction networks with phenotypes reveals signs of interactions.Curation accuracy of model organism databasesThe ConsensusPathDB interaction database: 2013 update.Network features suggest new hepatocellular carcinoma treatment strategiesSignaLink 2 - a signaling pathway resource with multi-layered regulatory networksInterpretation of genomic variants using a unified biological network approach.Dynamics and structure in cell signaling networks: off-state stability and dynamically positive cycles.Role of SMC1A overexpression as a predictor of poor prognosis in late stage colorectal cancer.MetaNetVar: Pipeline for applying network analysis tools for genomic variants analysis.ASD v3.0: unraveling allosteric regulation with structural mechanisms and biological networks.DL-3-n-butylphthalide delays the onset and progression of diabetic cataract by inhibiting oxidative stress in rat diabetic model.Identification of critical paralog groups with indispensable roles in the regulation of signaling flow.Integrating fragmented software applications into holistic solutions: focus on drug discovery.Endosomal crosstalk: meeting points for signaling pathways.Targeting molecular networks for drug researchLiverAtlas: a unique integrated knowledge database for systems-level research of liver and hepatic disease.Intracellular and intercellular signaling networks in cancer initiation, development and precision anti-cancer therapy: RAS acts as contextual signaling hub.Next generation of network medicine: interdisciplinary signaling approaches.Integrative analysis of ocular complications in atherosclerosis unveils pathway convergence and crosstalk.NRF2-ome: an integrated web resource to discover protein interaction and regulatory networks of NRF2.Mining large-scale response networks reveals 'topmost activities' in Mycobacterium tuberculosis infection.Signaling hypergraphs.Sulforaphane-induced transcription of thioredoxin reductase in lens: possible significance against cataract formation.VEGF-A/VEGFR2 signaling network in endothelial cells relevant to angiogenesis.SalmoNet, an integrated network of ten Salmonella enterica strains reveals common and distinct pathways to host adaptation.Deciphering the cause of evolutionary variance within intrinsically disordered regions in human proteins.The NRF2-related interactome and regulome contain multifunctional proteins and fine-tuned autoregulatory loops.Finding co-mutated genes and candidate cancer genes in cancer genomes by stratified false discovery rate control.Analysis of pathway mutation profiles highlights collaboration between cancer-associated superpathways.Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury.
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Uniformly curated signaling pathways reveal tissue-specific cross-talks and support drug target discovery.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 June 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Uniformly curated signaling pa ...... support drug target discovery.
@en
Uniformly curated signaling pa ...... support drug target discovery.
@nl
type
label
Uniformly curated signaling pa ...... support drug target discovery.
@en
Uniformly curated signaling pa ...... support drug target discovery.
@nl
prefLabel
Uniformly curated signaling pa ...... support drug target discovery.
@en
Uniformly curated signaling pa ...... support drug target discovery.
@nl
P2093
P356
P1433
P1476
Uniformly curated signaling pa ...... support drug target discovery
@en
P2093
Csaba Böde
Katalin Lenti
Máté S Szalay
Petra Rovó
Péter Csermely
Tamás Korcsmáros
Tibor Vellai
Zoltán Spiró
P304
P356
10.1093/BIOINFORMATICS/BTQ310
P407
P577
2010-06-11T00:00:00Z