Phospholipase A2 and arachidonic acid in Alzheimer's disease
about
Characterizing the network of drugs and their affected metabolic subpathwaysIdentification of distant drug off-targets by direct superposition of binding pocket surfacesSmall molecule analysis and imaging of fatty acids in the zebra finch song system using time-of-flight-secondary ion mass spectrometryCellular lipid extraction for targeted stable isotope dilution liquid chromatography-mass spectrometry analysisAPOE ε4 specific imbalance of arachidonic acid and docosahexaenoic acid in serum phospholipids identifies individuals with preclinical Mild Cognitive Impairment/Alzheimer's Disease.Oxidative-stress induced increase in circulating fatty acids does not contribute to phospholipase A2-dependent appetitive long-term memory failure in the pond snail Lymnaea stagnalis.Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids.Increase of cytosolic phospholipase A2 as hydrolytic enzyme of phospholipids and autism cognitive, social and sensory dysfunction severity.Role of cytosolic phospholipase A2 in oxidative and inflammatory signaling pathways in different cell types in the central nervous systemPhospholipase A2 - nexus of aging, oxidative stress, neuronal excitability, and functional decline of the aging nervous system? Insights from a snail model system of neuronal aging and age-associated memory impairmentPhospholipases A2 and neural membrane dynamics: implications for Alzheimer's disease.Evidence for inflammation-mediated memory dysfunction in gastropods: putative PLA2 and COX inhibitors abolish long-term memory failure induced by systemic immune challenges.Mass Spectrometry-based Lipidomics and Its Application to Biomedical ResearchSynaptic and extrasynaptic NMDA receptors differentially modulate neuronal cyclooxygenase-2 function, lipid peroxidation, and neuroprotection.Axonal gradient of arachidonic acid-containing phosphatidylcholine and its dependence on actin dynamics.Linking lipids to Alzheimer's disease: cholesterol and beyond.Integrating cytosolic phospholipase A₂ with oxidative/nitrosative signaling pathways in neurons: a novel therapeutic strategy for AD.White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease.Serum Metabolic Profiling Reveals Altered Metabolic Pathways in Patients with Post-traumatic Cognitive Impairments.Wide-ranging alterations in the brain fatty acid complement of subjects with late Alzheimer's disease as detected by GC-MSReduction of synaptojanin 1 ameliorates synaptic and behavioral impairments in a mouse model of Alzheimer's disease.Blood metabolite markers of cognitive performance and brain function in aging.Heart fatty acid binding protein and Aβ-associated Alzheimer's neurodegeneration.BACE1 RNAi Restores the Composition of Phosphatidylethanolamine-Derivates Related to Memory Improvement in Aged 3xTg-AD Mice.Early Transcriptional Changes Induced by Wnt/β-Catenin Signaling in Hippocampal NeuronsIntegration of transient receptor potential canonical channels with lipids.Lipidomics of Alzheimer's disease: current status.Role of cytosolic calcium-dependent phospholipase A2 in Alzheimer's disease pathogenesis.The omega-6/omega-3 ratio and dementia or cognitive decline: a systematic review on human studies and biological evidence.Inhibition of arachidonate 15-lipoxygenase prevents 4-hydroxynonenal-induced protein damage in male germ cells.Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A2 in a spatial-specific manner.Hippocampal metabolomics using ultrahigh-resolution mass spectrometry reveals neuroinflammation from Alzheimer's disease in CRND8 mice.A UPLC-TOF/MS-based metabolomics study of rattan stems of Schisandra chinensis effects on Alzheimer's disease rats model.A cellular lipidomic study on the Aβ-induced neurotoxicity and neuroprotective effects of EGCG by using UPLC/MS-based glycerolipids profiling and multivariate analysis.Dietary eicosapentaenoic acid normalizes hippocampal omega-3 and 6 polyunsaturated fatty acid profile, attenuates glial activation and regulates BDNF function in a rodent model of neuroinflammation induced by central interleukin-1β administration.Plasmalogens inhibit APP processing by directly affecting γ-secretase activity in Alzheimer's disease.Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease.Short-Term Fish Oil Treatment Changes the Composition of Phospholipids While Not Affecting the Expression of Mfsd2a Omega-3 Transporter in the Brain and Liver of the 5xFAD Mouse Model of Alzheimer's DiseaseTargeted metabolomics reveals altered oxylipin profiles in plasma of mild cognitive impairment patients
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Phospholipase A2 and arachidonic acid in Alzheimer's disease
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 May 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Phospholipase A2 and arachidonic acid in Alzheimer's disease
@en
Phospholipase A2 and arachidonic acid in Alzheimer's disease.
@nl
type
label
Phospholipase A2 and arachidonic acid in Alzheimer's disease
@en
Phospholipase A2 and arachidonic acid in Alzheimer's disease.
@nl
prefLabel
Phospholipase A2 and arachidonic acid in Alzheimer's disease
@en
Phospholipase A2 and arachidonic acid in Alzheimer's disease.
@nl
P2860
P1476
Phospholipase A2 and arachidonic acid in Alzheimer's disease
@en
P2093
Lennart Mucke
Rene O Sanchez-Mejia
P2860
P304
P356
10.1016/J.BBALIP.2010.05.013
P407
P577
2010-05-27T00:00:00Z