The interrelationship between mitochondrial dysfunction and transcriptional dysregulation in Huntington disease.
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Dysregulation of glutathione homeostasis in neurodegenerative diseasesImpaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtinA novel multiplex cell viability assay for high-throughput RNAi screeningThe neuroprotective effect of Klotho is mediated via regulation of members of the redox system.Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ.Huntington's Disease: From Mutant Huntingtin Protein to Neurotrophic Factor Therapy.Crude extract of Euphorbia formosana induces apoptosis of DU145 human prostate cancer cells acts through the caspase-dependent and independent signaling pathway.trans-(-)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease.Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease.Targeting H3K4 trimethylation in Huntington diseaseAn Intrabody Drug (rAAV6-INT41) Reduces the Binding of N-Terminal Huntingtin Fragment(s) to DNA to Basal Levels in PC12 Cells and Delays Cognitive Loss in the R6/2 Animal ModelHypoxia inducible factor-1 as a target for neurodegenerative diseases.DEFOG: discrete enrichment of functionally organized genes.Does PGC1α/FNDC5/BDNF Elicit the Beneficial Effects of Exercise on Neurodegenerative Disorders?Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).Whole gene expression profile in blood reveals multiple pathways deregulation in R6/2 mouse model.Combining membrane proteomics and computational three-way pathway analysis revealed signalling pathways preferentially regulated in human iPSCs and human ESCs.Role of Quercetin Benefits in Neurodegeneration.A genetic modifier suggests that endurance exercise exacerbates Huntington's disease.Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease
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The interrelationship between mitochondrial dysfunction and transcriptional dysregulation in Huntington disease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on June 2010
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The interrelationship between ...... ulation in Huntington disease.
@en
The interrelationship between ...... ulation in Huntington disease.
@nl
type
label
The interrelationship between ...... ulation in Huntington disease.
@en
The interrelationship between ...... ulation in Huntington disease.
@nl
prefLabel
The interrelationship between ...... ulation in Huntington disease.
@en
The interrelationship between ...... ulation in Huntington disease.
@nl
P2860
P1476
The interrelationship between ...... ulation in Huntington disease.
@en
P2093
Gail V W Johnson
Youngnam N Jin
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P2888
P304
P356
10.1007/S10863-010-9286-7
P577
2010-06-01T00:00:00Z