Therapeutic approaches to epileptogenesis--hope on the horizon.
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Identification of new epilepsy treatments: issues in preclinical methodologyBlood-brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsyElectrophysiological biomarkers of epilepsy.Epilepsy related to traumatic brain injury.Issues related to development of antiepileptogenic therapies.Anti-epileptogenic clinical trial designs in epilepsy: issues and optionsModern antiepileptic drug development has failed to deliver: ways out of the current dilemma.Upregulation of adenosine kinase in astrocytes in experimental and human temporal lobe epilepsyInfluence of aspirin on pilocarpine-induced epilepsy in mice.Transient inhibition of TrkB kinase after status epilepticus prevents development of temporal lobe epilepsy.The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments.A Peptide Uncoupling BDNF Receptor TrkB from Phospholipase Cγ1 Prevents Epilepsy Induced by Status EpilepticusAntiepileptogenic and Neuroprotective Effects of Pergularia daemia on Pilocarpine Model of Epilepsy.Dynamic expression patterns of ATF3 and p53 in the hippocampus of a pentylenetetrazole-induced kindling model.Hippocampal MRI and other structural biomarkers: experimental approach to epileptogenesis.Finding a better drug for epilepsy: preclinical screening strategies and experimental trial design.Prevention or modification of epileptogenesis after brain insults: experimental approaches and translational research.Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish.Defining "epileptogenesis" and identifying "antiepileptogenic targets" in animal models of acquired temporal lobe epilepsy is not as simple as it might seem.Opening Pandora's jar: a primer on the putative roles of CRMP2 in a panoply of neurodegenerative, sensory and motor neuron, and central disorders.Brain inflammation as a biomarker in epilepsy.Interictal spikes, seizures and ictal cell death are not necessary for post-traumatic epileptogenesis in vitroDisease-modifying effect of intravenous immunoglobulin in an experimental model of epilepsy.Past and present definitions of epileptogenesis and its biomarkers.Biomarkers in epilepsy: introduction.Histamine H3 receptor antagonists in relation to epilepsy and neurodegeneration: a systemic consideration of recent progress and perspectives.The mTOR signaling pathway in the brain: focus on epilepsy and epileptogenesis.Impact of the neural cell adhesion molecule-derived peptide FGL on seizure progression and cellular alterations in the mouse kindling model.Circadian clustering of spontaneous epileptic seizures emerges after pilocarpine-induced status epilepticus.Tuberous sclerosis complex as a model disease for developing new therapeutics for epilepsy.Exploring the latest avenues for antiepileptic drug discovery and development.Neuronal network models of epileptogenesis.Lacosamide treatment following status epilepticus attenuates neuronal cell loss and alterations in hippocampal neurogenesis in a rat electrical status epilepticus model.Epilepsy treatment: a paradigm shift is urgently need.Tubulin β-III modulates seizure activity in epilepsy.Antiepileptic prophylaxis following severe traumatic brain injury within a military cohort.Effect of eugenol on lithium-pilocarpine model of epilepsy: behavioral, histological, and molecular changes.Synthesis of a FTO inhibitor with anticonvulsant activity.Posttraumatic Epilepsy: What's Contusion Got to Do With It?Decreased expression of Gab2 in patients with temporal lobe epilepsy and pilocarpine-induced rat model.
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Therapeutic approaches to epileptogenesis--hope on the horizon.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on July 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Therapeutic approaches to epileptogenesis--hope on the horizon.
@en
Therapeutic approaches to epileptogenesis--hope on the horizon.
@nl
type
label
Therapeutic approaches to epileptogenesis--hope on the horizon.
@en
Therapeutic approaches to epileptogenesis--hope on the horizon.
@nl
prefLabel
Therapeutic approaches to epileptogenesis--hope on the horizon.
@en
Therapeutic approaches to epileptogenesis--hope on the horizon.
@nl
P2860
P1433
P1476
Therapeutic approaches to epileptogenesis--hope on the horizon.
@en
P2093
Asla Pitkänen
P2860
P356
10.1111/J.1528-1167.2010.02602.X
P478
51 Suppl 3
P577
2010-07-01T00:00:00Z