NF-κB inducing kinase: a key regulator in the immune system and in cancer
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The Emerging Role of miRNAs in HTLV-1 Infection and ATLL PathogenesisStructure of the Nuclear Factor B-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active ConformationArsenic trioxide exerts antimyeloma effects by inhibiting activity in the cytoplasmic substrates of histone deacetylase 6NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signalingThe relationship between members of the canonical NF-κB pathway, components of tumour microenvironment and survival in patients with invasive ductal breast cancerNF-κB inducing kinase, NIK mediates cigarette smoke/TNFα-induced histone acetylation and inflammation through differential activation of IKKs.Limitation of immune tolerance-inducing thymic epithelial cell development by Spi-B-mediated negative feedback regulationDownregulation of TRAF2 mediates NIK-induced pancreatic cancer cell proliferation and tumorigenicityMouse hepatocyte overexpression of NF-κB-inducing kinase (NIK) triggers fatal macrophage-dependent liver injury and fibrosis.NF-κB and cancer: a paradigm of Yin-Yang.The complex interplay between autophagy and NF-κB signaling pathways in cancer cellsBovine lactoferrin free of lipopolysaccharide can induce a proinflammatory response of macrophagesA roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses.NF-κB–inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon actionA cell-intrinsic requirement for NF-κB-inducing kinase in CD4 and CD8 T cell memory.Zinc finger protein 91 (ZFP91) activates HIF-1α via NF-κB/p65 to promote proliferation and tumorigenesis of colon cancer.NF-kappaΒ-inducing kinase regulates stem cell phenotype in breast cancer.Non-canonical NFκB mutations reinforce pro-survival TNF response in multiple myeloma through an autoregulatory RelB:p50 NFκB pathway.Gene-gene interaction of BLK, TNFSF4, TRAF1, TNFAIP3, and REL in systemic lupus erythematosusMolecular hallmarks of adult T cell leukemia.Mir-302c mediates influenza A virus-induced IFNβ expression by targeting NF-κB inducing kinase.Catalytic subunits of the phosphatase calcineurin interact with NF-κB-inducing kinase (NIK) and attenuate NIK-dependent gene expression.Downregulation of miR-518a-3p activates the NIK-dependent NF-κB pathway in colorectal cancer.NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathwaysInduction of the alternative NF-κB pathway by lymphotoxin αβ (LTαβ) relies on internalization of LTβ receptor.Noncanonical NF-κB activation by the oncoprotein Tio occurs through a nonconserved TRAF3-binding motif.Pharmacological Potential and Synthetic Approaches of Imidazo[4,5-b]pyridine and Imidazo[4,5-c]pyridine Derivatives.Mitogen-Activated Protein Kinase 14 Promotes AKI.NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-κB pathwayTargeting the alternative NF-κB pathway in pancreatic cancer: a new direction for therapy?APPL1 regulates basal NF-κB activity by stabilizing NIK.Negative feedback regulation of NF-κB-inducing kinase is proteasome-dependent but does not require cellular inhibitors of apoptosis.NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion.NF-kB2 induces senescence bypass in melanoma via a direct transcriptional activation of EZH2.TBK1 suppression of IgA in the NIK of time.Immune-enhancing effect of Danggwibohyeoltang, an extract from Astragali Radix and Angelicae gigantis Radix, in vitro and in vivo.NF-κB-Mediated Inflammation in the Pathogenesis of Intracranial Aneurysm and Subarachnoid Hemorrhage. Does Autophagy Play a Role?The NF-κB Activating Pathways in Multiple Myeloma.Genomic associations with bill length and disease reveal drift and selection across island bird populationsAntitumorigenic effect of damnacanthal on melanoma cell viability through p53 and NF-κB/caspase-3 signaling pathways
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NF-κB inducing kinase: a key regulator in the immune system and in cancer
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 03 August 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
NF-κB inducing kinase: a key regulator in the immune system and in cancer
@en
NF-κB inducing kinase: a key regulator in the immune system and in cancer.
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type
label
NF-κB inducing kinase: a key regulator in the immune system and in cancer
@en
NF-κB inducing kinase: a key regulator in the immune system and in cancer.
@nl
prefLabel
NF-κB inducing kinase: a key regulator in the immune system and in cancer
@en
NF-κB inducing kinase: a key regulator in the immune system and in cancer.
@nl
P2860
P1476
NF-κB inducing kinase: a key regulator in the immune system and in cancer
@en
P2093
Ann Richmond
Yee Mon Thu
P2860
P304
P356
10.1016/J.CYTOGFR.2010.06.002
P577
2010-08-03T00:00:00Z