Germ cell mutagens: risk assessment challenges in the 21st century.
about
Chemical and biological work-related risks across occupations in Europe: a reviewPaternal lifestyle as a potential source of germline mutations transmitted to offspring.Sidestream tobacco smoke is a male germ cell mutagenUse of genetic toxicity data in GHS mutagenicity classification and labeling of substances.Transgenic rodent assay for quantifying male germ cell mutant frequency.Harnessing genomics to identify environmental determinants of heritable disease.Applying the erythrocyte Pig-a assay concept to rat epididymal sperm for germ cell mutagenicity evaluation.Dose-response mutation and spectrum analyses reveal similar responses at two microsatellite loci in benzo(a)pyrene-exposed mouse spermatogonia.Declaring the existence of human germ-cell mutagens.Development of the adverse outcome pathway "alkylation of DNA in male premeiotic germ cells leading to heritable mutations" using the OECD's users' handbook supplement.The development of adverse outcome pathways for mutagenic effects for the organization for economic co-operation and development
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Germ cell mutagens: risk assessment challenges in the 21st century.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on October 2010
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Germ cell mutagens: risk assessment challenges in the 21st century.
@en
Germ cell mutagens: risk assessment challenges in the 21st century.
@nl
type
label
Germ cell mutagens: risk assessment challenges in the 21st century.
@en
Germ cell mutagens: risk assessment challenges in the 21st century.
@nl
prefLabel
Germ cell mutagens: risk assessment challenges in the 21st century.
@en
Germ cell mutagens: risk assessment challenges in the 21st century.
@nl
P2860
P356
P1476
Germ cell mutagens: risk assessment challenges in the 21st century
@en
P2093
Timothy M Singer
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P304
P356
10.1002/EM.20613
P577
2010-10-01T00:00:00Z