1,3-Butadiene: I. Review of metabolism and the implications to human health risk assessment.
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Mercapturic acids: recent advances in their determination by liquid chromatography/mass spectrometry and their use in toxicant metabolism studies and in occupational and environmental exposure studiesStructures of Exocyclic R,R - and S,S - N 6 , N 6 -(2,3-Dihydroxybutan-1,4-diyl)-2′-Deoxyadenosine Adducts Induced by 1,2,3,4-Diepoxybutane1,3-Butadiene-Induced Adenine DNA Adducts Are Genotoxic but Only Weakly Mutagenic When Replicated in Escherichia coli of Various Repair and Replication BackgroundsMajor groove orientation of the (2S)-N(6)-(2-hydroxy-3-buten-1-yl)-2'-deoxyadenosine DNA adduct induced by 1,2-epoxy-3-butene.Alcohol dehydrogenase- and rat liver cytosol-dependent bioactivation of 1-chloro-2-hydroxy-3-butene to 1-chloro-3-buten-2-one, a bifunctional alkylating agent.Tobacco smoke-related health effects induced by 1,3-butadiene and strategies for risk reduction.Formation of fused-ring 2'-deoxycytidine adducts from 1-chloro-3-buten-2-one, an in vitro 1,3-butadiene metabolite, under in vitro physiological conditions.Potential roles of myeloperoxidase and hypochlorous acid in metabolism and toxicity of alkene hydrocarbons and drug molecules containing olefinic moieties.Modeling Pharmacokinetics.1,3-Butadiene-induced mitochondrial dysfunction is correlated with mitochondrial CYP2E1 activity in Collaborative Cross mice.Toxicological Implications of Mitochondrial Localization of CYP2E1.
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1,3-Butadiene: I. Review of metabolism and the implications to human health risk assessment.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on October 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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1,3-Butadiene: I. Review of me ...... human health risk assessment.
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1,3-Butadiene: I. Review of me ...... human health risk assessment.
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1,3-Butadiene: I. Review of me ...... human health risk assessment.
@en
1,3-Butadiene: I. Review of me ...... human health risk assessment.
@nl
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1,3-Butadiene: I. Review of me ...... human health risk assessment.
@en
1,3-Butadiene: I. Review of me ...... human health risk assessment.
@nl
P2093
P2860
P1476
1,3-Butadiene: I. Review of me ...... human health risk assessment.
@en
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Christopher R Kirman
Michael L Gargas
Richard J Albertini
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P356
10.3109/10408444.2010.507181
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P478
40 Suppl 1
P577
2010-10-01T00:00:00Z