The insulin-like growth factor signaling pathway as a target for treatment of colorectal carcinoma.
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miR-493 induction during carcinogenesis blocks metastatic settlement of colon cancer cells in liver.From genotype to functional phenotype: unraveling the metabolomic features of colorectal cancer.Reduced insulin-like growth factor I receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk.Anticancer activity of the type I insulin-like growth factor receptor antagonist, ganitumab, in combination with the death receptor 5 agonist, conatumumab.Identification of candidate serum proteins for classifying well-differentiated small intestinal neuroendocrine tumorsGenomic and molecular characterization of malignant peripheral nerve sheath tumor identifies the IGF1R pathway as a primary target for treatment.BRCA1 negatively regulates IGF-1 expression through an estrogen-responsive element-like siteEpigenomic program of Barrett's-associated neoplastic progression reveals possible involvement of insulin signaling pathways.Impact of targeting insulin-like growth factor signaling in head and neck cancers.Insulin-like growth factor 1 regulates growth of endometrial carcinoma through PI3k signaling pathway in insulin-resistant type 2 diabetesFormal modeling and analysis of ER-α associated Biological Regulatory Network in breast cancer.Maternal high-fat diet induces hyperproliferation and alters Pten/Akt signaling in prostates of offspring.The type 1 insulin-like growth factor receptor signalling system and targeted tyrosine kinase inhibition in cancer.Regulation of insulin-like growth factor 1 receptor signaling by microRNA-4458 in the development of lumbar disc degenerationInsulin-like growth factor 1 promotes growth of gastric cancer by inhibiting foxo1 nuclear retention.In vivo analysis of insulin-like growth factor type 1 receptor humanized monoclonal antibody MK-0646 and small molecule kinase inhibitor OSI-906 in colorectal cancer.Insulin-like growth factor 1 antagonizes lumbar disc degeneration through enhanced autophagy.IGF-1 protects tubular epithelial cells during injury via activation of ERK/MAPK signaling pathway.Tumour growth stimulation following partial hepatectomy in mice is associated with increased upregulation of c-Met.Pathway enrichment analysis approach based on topological structure and updated annotation of pathway.Microarray pathway analysis indicated that mitogen-activated protein kinase/extracellular signal-regulated kinase and insulin growth factor 1 signaling pathways were inhibited by small interfering RNA against AT-rich interactive domain 1A in endomet
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The insulin-like growth factor signaling pathway as a target for treatment of colorectal carcinoma.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on October 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The insulin-like growth factor ...... tment of colorectal carcinoma.
@en
The insulin-like growth factor ...... tment of colorectal carcinoma.
@nl
type
label
The insulin-like growth factor ...... tment of colorectal carcinoma.
@en
The insulin-like growth factor ...... tment of colorectal carcinoma.
@nl
prefLabel
The insulin-like growth factor ...... tment of colorectal carcinoma.
@en
The insulin-like growth factor ...... tment of colorectal carcinoma.
@nl
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P1476
The insulin-like growth factor ...... tment of colorectal carcinoma.
@en
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Gideon P Ewing
Laura W Goff
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P356
10.3816/CCC.2010.N.032
P407
P577
2010-10-01T00:00:00Z