Novel CRTH2 antagonists: a review of patents from 2006 to 2009. - Wikidata - awgldk - TriplyDB

Novel CRTH2 antagonists: a review of patents from 2006 to 2009.

Novel CRTH2 antagonists: a review of patents from 2006 to 2009.

http://www.wikidata.org/entity/Q37800109

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Profiling of differentially expressed genes using suppression subtractive hybridization in an equine model of chronic asthma Single- and multiple-dose tolerability and pharmacokinetics of the CRTH2 antagonist setipiprant in healthy male subjects.Pharmacokinetics, Safety, and Tolerability of Fevipiprant (QAW039), a Novel CRTh2 Receptor Antagonist: Results From 2 Randomized, Phase 1, Placebo-Controlled Studies in Healthy Volunteers.Atopic dermatitis and the nervous system.A novel DP2 receptor antagonist (AM-461): a patent evaluation of WO2011085033.Novel prostaglandin receptor modulators: a patent review (2002 - 2012) - part I: non-EP receptor modulators.The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies.Biochemical and pharmacological characterization of AZD1981, an orally available selective DP2 antagonist in clinical development for asthma.Optimization of the Central Core of Indolinone-Acetic Acid-Based CRTH2 (DP2) Receptor Antagonists.Benzodiazepinone Derivatives as CRTH2 Antagonists Discovery of a Novel Series of CRTH2 (DP2) Receptor Antagonists Devoid of Carboxylic Acids.Evaluation of WO2012078210--development process for the preparation of a DP2 receptor antagonist; Ironwood's first development DP2 antagonist.

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Novel CRTH2 antagonists: a review of patents from 2006 to 2009.

http://www.wikidata.org/entity/Q37800109

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 15 October 2010

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Novel CRTH2 antagonists: a review of patents from 2006 to 2009.

@en

Novel CRTH2 antagonists: a review of patents from 2006 to 2009.

@nl

type

label

Novel CRTH2 antagonists: a review of patents from 2006 to 2009.

@en

Novel CRTH2 antagonists: a review of patents from 2006 to 2009.

@nl

prefLabel

Novel CRTH2 antagonists: a review of patents from 2006 to 2009.

@en

Novel CRTH2 antagonists: a review of patents from 2006 to 2009.

@nl

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13543776.2010.525506

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Expert Opinion on Therapeutic Patents

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Novel CRTH2 antagonists: a review of patents from 2006 to 2009.

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Evi Kostenis

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Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

Cutting edge: agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2

Expression and molecular pharmacology of the mouse CRTH2 receptor

Activation of the prostaglandin D2 receptor DP2/CRTH2 increases allergic inflammation in mouse

The role of the prostaglandin D2 receptor, DP, in eosinophil trafficking

Sequence variants of the gene encoding chemoattractant receptor expressed on Th2 cells (CRTH2) are associated with asthma and differentially influence mRNA stability

On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2

Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2.

Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 1.

An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro.

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