Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome.
about
Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal- and glyoxal-glycated cysteine, arginine, and lysine residuesSite-specific AGE modifications in the extracellular matrix: a role for glyoxal in protein damage in diabetesNonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylasesMethylglyoxal: An Emerging Signaling Molecule in Plant Abiotic Stress Responses and ToleranceGlyoxalase 1-419C>A variant is associated with oxidative stress: implications in prostate cancer progressionNa+/H+-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosisComprehensive analysis of maillard protein modifications in human lenses: effect of age and cataractExtending the spectrum of α-dicarbonyl compounds in vivo.On the Relationship between Energy Metabolism, Proteostasis, Aging and Parkinson's Disease: Possible Causative Role of Methylglyoxal and Alleviative Potential of Carnosine.Glyoxalase 1 expression is associated with an unfavorable prognosis of oropharyngeal squamous cell carcinomaDifferential response to α-oxoaldehydes in tamoxifen resistant MCF-7 breast cancer cells.Glyoxalase I inhibition induces apoptosis in irradiated MCF-7 cells via a novel mechanism involving Hsp27, p53 and NF-κB.Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypesThe cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.Arginine-directed glycation and decreased HDL plasma concentration and functionalityA novel controllable hydrogen sulfide-releasing molecule protects human skin keratinocytes against methylglyoxal-induced injury and dysfunction.Methylglyoxal as a new biomarker in patients with septic shock: an observational clinical study.Methylglyoxal, the dark side of glycolysisGlucose autoxidation induces functional damage to proteins via modification of critical arginine residuesDetoxification of aldehydes by histidine-containing dipeptides: from chemistry to clinical implicationsPenicillium chrysogenum as a model system for studying cellular effects of methylglyoxal.Low-molecular-weight chitosan scavenges methylglyoxal and N (ε)-(carboxyethyl)lysine, the major factors contributing to the pathogenesis of nephropathy.Glutathione homeostasis and functions: potential targets for medical interventionsNatural history of age-related retinal lesions that precede AMD in mice fed high or low glycemic index diets.Role of advanced glycation endproducts and glyoxalase I in diabetic peripheral sensory neuropathy.Linagliptin Ameliorates Methylglyoxal-Induced Peritoneal Fibrosis in MiceSite specific modification of the human plasma proteome by methylglyoxal.Role of Glyoxalase 1 (Glo1) and methylglyoxal (MG) in behavior: recent advances and mechanistic insights.Restoration of glyoxalase enzyme activity precludes cognitive dysfunction in a mouse model of Alzheimer's disease.Dicarbonyls and glyoxalase in disease mechanisms and clinical therapeutics5'-O-Alkylpyridoxamines: Lipophilic Analogues of Pyridoxamine Are Potent Scavengers of 1,2-Dicarbonyls.Methylglyoxal suppresses human colon cancer cell lines and tumor growth in a mouse model by impairing glycolytic metabolism of cancer cells associated with down-regulation of c-Myc expression.Knockdown of glyoxalase 1 mimics diabetic nephropathy in nondiabetic mice.Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage.Control limits for accumulation of plant metabolites: brute force is no substitute for understanding.Non-enzymatic glycation and glycoxidation protein products in foods and diseases: an interconnected, complex scenario fully open to innovative proteomic studies.Dicarbonyl proteome and genome damage in metabolic and vascular disease.Dicarbonyl stress and glyoxalases in ovarian function.Assay of methylglyoxal and glyoxal and control of peroxidase interference.Glyoxalase I (Glo1) and its metabolites in vascular disease.
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Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 October 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome.
@en
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome.
@nl
type
label
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome.
@en
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome.
@nl
prefLabel
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome.
@en
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome.
@nl
P1433
P1476
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome.
@en
P2093
Naila Rabbani
P2888
P304
P356
10.1007/S00726-010-0783-0
P577
2010-10-21T00:00:00Z