The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in β-cells.
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Oxidative Stress in the Healthy and Wounded Hepatocyte: A Cellular Organelles PerspectiveEndoplasmic reticulum stress and type 2 diabetesEndoplasmic reticulum stress in the β-cell pathogenesis of type 2 diabetesLost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitusEnergy metabolism in the liverTranslational control mechanisms in metabolic regulation: critical role of RNA binding proteins, microRNAs, and cytoplasmic RNA granulesStanniocalcin 2 is a negative modulator of store-operated calcium entryFree cysteine modulates the conformation of human C/EBP homologous proteinOsDGL1, a homolog of an oligosaccharyltransferase complex subunit, is involved in N-glycosylation and root development in rice.Unfolded protein response is required for the definitive endodermal specification of mouse embryonic stem cells via Smad2 and β-catenin signaling.Maintenance of Pdx1 mRNA translation in islet β-cells during the unfolded protein response.Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type miceActivating transcription factor 6 limits intracellular accumulation of mutant α(1)-antitrypsin Z and mitochondrial damage in hepatoma cells.Metabolic stress in autophagy and cell death pathwaysType I interferons mediate pancreatic toxicities of PERK inhibition.Hyperactivity of the Ero1α oxidase elicits endoplasmic reticulum stress but no broad antioxidant response.Group VIB Phospholipase A(2) promotes proliferation of INS-1 insulinoma cells and attenuates lipid peroxidation and apoptosis induced by inflammatory cytokines and oxidant agentsEndoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathyThe unfolded protein response to endoplasmic reticulum stress in cultured astrocytes and rat brain during experimental diabetes.Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in β-cell gene expression and progression to diabetesA self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux.Obesity, insulin resistance, and metabolic syndrome: a study in WNIN/Ob rats from a pancreatic perspectiveIn vivo Investigation of Anti-diabetic Properties of Ripe Onion Juice in Normal and Streptozotocin-induced Diabetic Rats.Gaucher disease paradigm: from ERAD to comorbidity.Diabetes and beta cell function: from mechanisms to evaluation and clinical implications.Postprandial Dysmetabolism and Oxidative Stress in Type 2 Diabetes: Pathogenetic Mechanisms and Therapeutic Strategies.Peroxisome Proliferator-activated Receptor-γ Activation Augments the β-Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and β Cell Death in Non-obese Diabetic MiceCircadian variation of the pancreatic islet transcriptome.Metabolic control of the proteotoxic stress response: implications in diabetes mellitus and neurodegenerative disorders.Association between telomere length and diabetes mellitus: A meta-analysis.New Directions in Gaucher Disease.IRE1-dependent activation of AMPK in response to nitric oxide.Unfolded protein response in Gaucher disease: from human to Drosophila.Arsenite-induced autophagy is associated with proteotoxicity in human lymphoblastoid cells.Cross-talk between the unfolded protein response and nuclear factor-κB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets.Posttranslational modifications of proteins in type 1 diabetes: the next step in finding the cure?EIF2S3 Mutations Associated with Severe X-Linked Intellectual Disability Syndrome MEHMO.Acute lymphoblastic leukemia cells are sensitive to disturbances in protein homeostasis induced by proteasome deubiquitinase inhibitionHydrogen sulfide ameliorates cognitive dysfunction in streptozotocin-induced diabetic rats: involving suppression in hippocampal endoplasmic reticulum stressProtective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway.
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The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in β-cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The unfolded protein response ...... ve differentiation in β-cells.
@en
The unfolded protein response ...... ve differentiation in β-cells.
@nl
type
label
The unfolded protein response ...... ve differentiation in β-cells.
@en
The unfolded protein response ...... ve differentiation in β-cells.
@nl
prefLabel
The unfolded protein response ...... ve differentiation in β-cells.
@en
The unfolded protein response ...... ve differentiation in β-cells.
@nl
P2093
P2860
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P1476
The unfolded protein response ...... ve differentiation in β-cells.
@en
P2093
P2860
P304
P356
10.1111/J.1463-1326.2010.01281.X
P478
12 Suppl 2
P5008
P577
2010-10-01T00:00:00Z