Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies.
about
Quality Issues of Research Antibodies.A universal surrogate peptide to enable LC-MS/MS bioanalysis of a diversity of human monoclonal antibody and human Fc-fusion protein drug candidates in pre-clinical animal studies.Toward sensitive and accurate analysis of antibody biotherapeutics by liquid chromatography coupled with mass spectrometry.Advances and challenges in analytical characterization of biotechnology products: mass spectrometry-based approaches to study properties and behavior of protein therapeuticsGlycome characterization of immunoglobulin G from buffalo (Bubalus bubalis) colostrum.Impact of disease on interferences in blood bioanalysis.Absolute quantitation of protein therapeutics in biological matrices by enzymatic digestion and LC-MS.Monoclonal antibodies: what are the pharmacokinetic and pharmacodynamic considerations for drug development?Application and challenges in using LC-MS assays for absolute quantitative analysis of therapeutic proteins in drug discovery.Quantitation of human peptides and proteins via MS: review of analytically validated assays.Antibody-free workflows for protein quantification by LC-MS/MS.Quantification of biopharmaceuticals and biomarkers in complex biological matrices: a comparison of liquid chromatography coupled to tandem mass spectrometry and ligand binding assays.Quantitative MS analysis of therapeutic mAbs and their glycosylation for pharmacokinetics study.Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.Ultrasensitive bioanalysis: current status and future trends.Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry.Evaluation of Gallium as a Tracer of Exogenous Hemoglobin-Haptoglobin Complexes for Targeted Drug Delivery Applications.Absolute and multiplex quantification of antibodies in serum using PSAQ™ standards and LC-MS/MS.Nano-scale liquid chromatography/mass spectrometry and on-the-fly orthogonal array optimization for quantification of therapeutic monoclonal antibodies and the application in preclinical analysis.An exploratory universal LC-MS/MS assay for bioanalysis of hinge region-stabilized human IgG4 mAbs in clinical studies.Quantification of human mAbs in mouse tissues using generic affinity enrichment procedures and LC-MS detection.Do we have a mature LC-MS/MS methodology for therapeutic monoclonal antibody bioanalysis?PSAQ™ standards for accurate MS-based quantification of proteins: from the concept to biomedical applications.LC-MS/MS strategies for therapeutic antibodies and investigation into the quantitative impact of antidrug-antibodies.Dual universal peptide approach to bioanalysis of human monoclonal antibody protein drug candidates in animal studies.Developing trends in bioanalysis.Feasibility assessment of a novel selective peptide derivatization strategy for sensitivity enhancement for the liquid chromatography/tandem mass spectrometry bioanalysis of protein therapeutics in serum.Hybridizing LBA with LC-MS/MS: the new norm for biologics quantification.
P2860
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P2860
Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies.
@en
Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies.
@nl
type
label
Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies.
@en
Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies.
@nl
prefLabel
Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies.
@en
Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies.
@nl
P2860
P356
P1433
P1476
Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies.
@en
P2093
Francis Bitsch
P2860
P304
P356
10.4155/BIO.09.121
P577
2009-11-01T00:00:00Z