SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model.
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Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTORStem cell guidance through the mechanistic target of rapamycinSIRT1 as a therapeutic target in inflammaging of the pulmonary diseaseProtein lysine acylation and cysteine succination by intermediates of energy metabolismMDCK cystogenesis driven by cell stabilization within computational analoguesAcetylation of yeast AMPK controls intrinsic aging independently of caloric restriction.Erythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life ExpectancySlowing ageing by design: the rise of NAD(+) and sirtuin-activating compoundsNicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from PellagraEndothelial SIRT1 prevents adverse arterial remodeling by facilitating HERC2-mediated degradation of acetylated LKB1.Licochalcone Suppresses LXRα-Induced Hepatic Lipogenic Gene Expression through AMPK/Sirt1 Pathway Activation.Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis.Leucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes.Proteasomes, Sir2, and Hxk2 form an interconnected aging network that impinges on the AMPK/Snf1-regulated transcriptional repressor Mig1.Role of AMP-Activated Protein Kinase (AMPK) in Smoking-Induced Lung Inflammation and Emphysema.A TagSNP in SIRT1 gene confers susceptibility to myocardial infarction in a Chinese Han population.Perspectives of Targeting mTORC1-S6K1 in Cardiovascular AgingHumulus japonicus extract exhibits antioxidative and anti-aging effects via modulation of the AMPK-SIRT1 pathwayPhenolic secoiridoids in extra virgin olive oil impede fibrogenic and oncogenic epithelial-to-mesenchymal transition: extra virgin olive oil as a source of novel antiaging phytochemicals.5-Aminoimidazole-4-carboxyamide ribonucleoside induces G(1)/S arrest and Nanog downregulation via p53 and enhances erythroid differentiationPerspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence.WISP1 neuroprotection requires FoxO3a post-translational modulation with autoregulatory control of SIRT1AMPK activation protects cells from oxidative stress-induced senescence via autophagic flux restoration and intracellular NAD(+) elevation.Constitutive activation of AMPK α1 in vascular endothelium promotes high-fat diet-induced fatty liver injury: role of COX-2 induction.SIRT1 promotes metastasis of human osteosarcoma cells.Sirtuin 6: a review of biological effects and potential therapeutic properties.Mitochondrial metabolic failure in telomere attrition-provoked aging of bone marrow mesenchymal stem cells.Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders.Endothelium-dependent hyperpolarization: age, gender and blood pressure, do they matter?Gerometabolites: the pseudohypoxic aging side of cancer oncometabolites.Reduction in podocyte SIRT1 accelerates kidney injury in aging mice.Harnessing the Power of SIRT1 and Non-coding RNAs in Vascular Disease.A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of human fibroblastic Hs68 cells via attenuation of NAD(+)-SIRT1 signaling.Reverse Expression of Aging-Associated Molecules through Transfection of miRNAs to Aged Mice.Autophagy regulating kinases as potential therapeutic targets for age-related macular degeneration.Lipid Accumulation in HepG2 Cells Is Attenuated by Strawberry Extract through AMPK Activation.Rehabilitation Training and Resveratrol Improve the Recovery of Neurological and Motor Function in Rats after Cerebral Ischemic Injury through the Sirt1 Signaling Pathway.Peroxisome Proliferator-Activated Receptor α Facilitates Osteogenic Differentiation in MC3T3-E1 Cells via the Sirtuin 1-Dependent Signaling Pathway.Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes.Reduced activity of SKC a and Na-K ATPase underlies the accelerated impairment of EDH-type relaxations in mesenteric arteries of aging spontaneously hypertensive rats.
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SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 02 December 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model.
@en
SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model.
@nl
type
label
SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model.
@en
SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model.
@nl
prefLabel
SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model.
@en
SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model.
@nl
P2860
P1433
P1476
SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model.
@en
P2093
P2860
P304
P356
10.1016/J.FEBSLET.2010.11.047
P407
P577
2010-12-02T00:00:00Z