Challenges in inhaled product development and opportunities for open innovation.
about
Morphometric Characterization of Rat and Human Alveolar Macrophage Cell Models and their Response to Amiodarone using High Content Image Analysis.In Vitro Assessment of Uptake and Lysosomal Sequestration of Respiratory Drugs in Alveolar Macrophage Cell Line NR8383Regulatory toxicology considerations for the development of inhaled pharmaceuticals.Strategies for non-invasive delivery of biologics.Computational analysis of non-spherical particle transport and deposition in shear flow with application to lung aerosol dynamics--a review.Inhaled biopharmaceutical drug development: nonclinical considerations and case studies.Mechanisms of absorption and elimination of drugs administered by inhalation.Foamy macrophage responses in the rat lung following exposure to inhaled pharmaceuticals: a simple, pragmatic approach for inhaled drug development.Toxicological perspectives of inhaled therapeutics and nanoparticles.Generation of tailored aerosols for inhalative drug delivery employing recent vibrating-mesh nebulizer systems.Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure SystemPharmacodynamic and pharmacokinetic assessment of fluticasone furoate + vilanterol for the treatment of asthma.Materials and methods for delivery of biological drugs.Systems Pharmacology Approach for Prediction of Pulmonary and Systemic Pharmacokinetics and Receptor Occupancy of Inhaled Drugs.Btk Inhibitor RN983 Delivered by Dry Powder Nose-only Aerosol Inhalation Inhibits Bronchoconstriction and Pulmonary Inflammation in the Ovalbumin Allergic Mouse Model of AsthmaSymposium Summary: "Breathe In, Breathe Out, Its Easy: What You Need to Know About Developing Inhaled Drugs".A Comparison of Drug Transport in Pulmonary Absorption Models: Isolated Perfused rat Lungs, Respiratory Epithelial Cell Lines and Primary Cell Culture.Pulmonary aerosol delivery and the importance of growth dynamics.The in vitro and in vivo investigation of a novel small chamber dry powder inhalation delivery system for preclinical dosing to rats.Perspective: Aerosol microphysics: From molecules to the chemical physics of aerosols.The Differential Absorption of a Series of P-Glycoprotein Substrates in Isolated Perfused Lungs from Mdr1a/1b Genetic Knockout Mice can be Attributed to Distinct Physico-Chemical Properties: an Insight into Predicting Transporter-Mediated, PulmonaryLost in translation: what is stopping inhaled nanomedicines from realizing their potential?Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals.Is there room for further innovation in inhaled therapy for airways disease?
P2860
Q30313151-AE6C4826-59D6-4A86-867F-3593CDDFD252Q36234390-6018942A-C8C2-42F1-9D52-85CCC2F560C5Q37978447-0AFA94A2-F1E3-4C3D-874C-E467B9DA31BEQ38013190-01F071FA-1F3D-44EB-8C2B-C8EA8F68CCCEQ38085036-097B88FE-DC1D-40F1-A3E3-A8ED98E15440Q38088303-B54524C7-E879-4EA2-A723-C5D8CC3CB79EQ38126941-119CA5C3-CAC5-4568-8DEC-B16F3E73C269Q38182903-8A6F38AE-7A33-4EC3-A2C4-62AAB0FFA461Q38210288-BC2C9981-FEEC-44DC-9179-3467C3E01168Q38498038-34C6640F-6FAB-4A74-9A00-203AD74D70A7Q38690308-EB001EB4-6C47-4B5B-AE0E-ABC17ED12A16Q38851423-16349098-DDF3-432B-B9DC-9A6D37A6C8ADQ38987392-4F470826-4697-4633-9EBE-70CF2D9EE7B5Q40258577-27645925-8332-4ED1-B4BE-F67AC7419DD2Q42329453-65FF8576-861C-440C-9F9F-0DA3F9D3920DQ46598765-38BA063B-8C20-4BD3-8E65-4835EFEA8235Q47107787-8056418D-1ECE-40E1-8B14-B137C1A6D8BCQ47362335-51A4B1B3-1228-41C5-A689-FF8F3089F996Q47641145-23A0A766-441C-412E-8091-E8204D6A3C64Q48108623-67D93337-A921-43E2-81F3-A8DFA3229797Q48134628-11C8DB8D-66A6-4582-B963-364A905A0E47Q51692769-D436D653-882A-44DE-9C67-59CB6624E5EFQ52573931-590AC44A-57AA-4064-913C-5BA661AABBA4Q58777102-30F1B2EB-B1F6-419B-8C12-76AB4C5D2BFF
P2860
Challenges in inhaled product development and opportunities for open innovation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 December 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Challenges in inhaled product development and opportunities for open innovation.
@en
Challenges in inhaled product development and opportunities for open innovation.
@nl
type
label
Challenges in inhaled product development and opportunities for open innovation.
@en
Challenges in inhaled product development and opportunities for open innovation.
@nl
prefLabel
Challenges in inhaled product development and opportunities for open innovation.
@en
Challenges in inhaled product development and opportunities for open innovation.
@nl
P2093
P1476
Challenges in inhaled product development and opportunities for open innovation.
@en
P2093
Bahman Asgharian
Ben Forbes
Colin Hardy
David Hassall
Douglas Ferguson
Gary R Pitcairn
Graham Somers
Janet Maas
Lea Ann Dailey
Lena Gustavsson
P356
10.1016/J.ADDR.2010.11.004
P407
P577
2010-12-06T00:00:00Z