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PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

http://www.wikidata.org/entity/Q37822920

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St John's Wort (Hypericum perforatum L.) photomedicine: hypericin-photodynamic therapy induces metastatic melanoma cell death YY1-binding sites provide central switch functions in the PARP-1 gene expression network Poly(ADP-ribose) polymerase-1 inhibition by arsenite promotes the survival of cells with unrepaired DNA lesions induced by UV exposure Balancing functions of annexin A6 maintain equilibrium between hypertrophy and apoptosis in cardiomyocytes Phenethyl isothiocyanate and paclitaxel synergistically enhanced apoptosis and alpha-tubulin hyperacetylation in breast cancer cells Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response Regulation of PI3K/Akt dependent apoptotic markers during b virus infection of human and macaque fibroblasts.Neuronal and astrocytic interactions modulate brain endothelial properties during metabolic stresses of in vitro cerebral ischemia.Combinational delivery of c-myc siRNA and nucleoside analogs in a single, synthetic nanocarrier for targeted cancer therapy.The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia Differential pro-apoptotic effects of synthetic 4-thiazolidinone derivative Les-3288, doxorubicin and temozolomide in human glioma U251 cells.Analysis of necroptotic proteins in failing human hearts.Characterizing the efficacy of fermented wheat germ extract against ovarian cancer and defining the genomic basis of its activity.Age-related homeostatic midchannel proteolysis of neuronal L-type voltage-gated Ca²⁺ channels.Anti-proliferative potential of Glucosamine in renal cancer cells via inducing cell cycle arrest at G0/G1 phase SIRT1 ameliorates oxidative stress induced neural cell death and is down-regulated in Parkinson's disease.Abrus agglutinin suppresses human hepatocellular carcinoma in vitro and in vivo by inducing caspase-mediated cell death.PARP1-driven apoptosis in chronic lymphocytic leukemia.RAD9 enhances radioresistance of human prostate cancer cells through regulation of ITGB1 protein levels.Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells High expression of Wee1 is associated with poor disease-free survival in malignant melanoma: potential for targeted therapy Autophagy and apoptosis are differentially induced in neurons and astrocytes treated with an in vitro mimic of the ischemic penumbra.Maintenance of melanophore morphology and survival is cathepsin and vps11 dependent in zebrafish.The multiple roles of sGP in Ebola pathogenesis Identification and validation of p50 as the cellular target of eriocalyxin B.Induction of cytopathogenicity in human glioblastoma cells by chikungunya virus.Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway.Phosphorylation of Merkel cell polyomavirus large tumor antigen at serine 816 by ATM kinase induces apoptosis in host cells.Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells.P2X7 receptor inhibition protects against ischemic acute kidney injury in mice.Heat-modified citrus pectin induces apoptosis-like cell death and autophagy in HepG2 and A549 cancer cells.Organometallic nucleosides induce non-classical leukemic cell death that is mitochondrial-ROS dependent and facilitated by TCL1-oncogene burden.Hydrogen-rich saline reduces cell death through inhibition of DNA oxidative stress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusion injury.Time-Point Dependent Activation of Autophagy and the UPS in SOD1G93A Mice Skeletal Muscle Ghrelin attenuates brain injury after traumatic brain injury and uncontrolled hemorrhagic shock in rats.Timing of cardiomyocyte growth, maturation, and attrition in perinatal sheep.Anti-apoptotic role and clinical relevance of neurotrophins in diffuse large B-cell lymphomas Association of Autophagy in the Cell Death Mediated by Dihydrotestosterone in Autoreactive T Cells Independent of Antigenic Stimulation.Theranostic etoposide phosphate/indium nanoparticles for cancer therapy and imaging.Enhancing therapeutic efficacy through designed aggregation of nanoparticles.

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PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

http://www.wikidata.org/entity/Q37822920

description

article científic

@ca

article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

@tr

scientific article published on 22 December 2010

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

@en

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration.

@nl

type

label

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

@en

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration.

@nl

prefLabel

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

@en

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration.

@nl

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Cell Communication and Signaling

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PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

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Alexander J Steven

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Ganta Vijay Chaitanya

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Phanithi Prakash Babu

http://www.w3.org/2001/XMLSchema#string

P2860

Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis

Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks

PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase

No death without life: vital functions of apoptotic effectors

XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

Granzymes: a family of lymphocyte granule serine proteases

m-Calpain is required for preimplantation embryonic development in mice.

A third zinc-binding domain of human poly(ADP-ribose) polymerase-1 coordinates DNA-dependent enzyme activation

Lysine acetylation targets protein complexes and co-regulates major cellular functions

Autolysis of human erythrocyte calpain produces two active enzyme forms with different cell localization

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31

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scholarly article

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10.1186/1478-811X-8-31

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8

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2010-12-22T00:00:00Z

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1017427406

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21176168

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3022541

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