A comprehensive map of the mTOR signaling network. - Wikidata - awgldk - TriplyDB

A comprehensive map of the mTOR signaling network.

A comprehensive map of the mTOR signaling network.

http://www.wikidata.org/entity/Q37823206

about

Charting the NF-κB pathway interactome map Mammalian target of rapamycin: a central node of complex signaling cascades The mTOR pathway in obesity driven gastrointestinal cancers: Potential targets and clinical trials Regulation of global and specific mRNA translation by the mTOR signaling pathway Signalling to eIF4E in cancer Molecular signaling network motifs provide a mechanistic basis for cellular threshold responses Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review The expanding role of mTOR in cancer cell growth and proliferation Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states.Computational modeling and analysis of insulin induced eukaryotic translation initiation Combining machine learning systems and multiple docking simulation packages to improve docking prediction reliability for network pharmacology Toward an integrated software platform for systems pharmacology Models of signalling networks - what cell biologists can gain from them and give to them Signalling pathway database usability: lessons learned.Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps The gastrin and cholecystokinin receptors mediated signaling network: a scaffold for data analysis and new hypotheses on regulatory mechanisms Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway.Quantitative phosphoproteomics of CXCL12 (SDF-1) signaling.Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries.Combined SFK/mTOR inhibition prevents rapamycin-induced feedback activation of AKT and elicits efficient tumor regression.Creating interactive, web-based and data-enriched maps with the Systems Biology Graphical Notation.AlzPathway: a comprehensive map of signaling pathways of Alzheimer's disease.In silico discovery of novel transcription factors regulated by mTOR-pathway activities.Evidence for mTOR pathway activation in a spectrum of epilepsy-associated pathologies.MODULATION OF AUTOPHAGY AND ITS POTENTIAL FOR CANCER THERAPY.BiNoM 2.0, a Cytoscape plugin for accessing and analyzing pathways using standard systems biology formats Wide coverage biomedical event extraction using multiple partially overlapping corpora.Primary cilia and coordination of receptor tyrosine kinase (RTK) signalling.A comprehensive map of the influenza A virus replication cycle Analytical reduction of combinatorial complexity arising from multiple protein modification sites.An Interaction Library for the FcεRI Signaling Network Primordial follicle activation in the ovary of Ames dwarf mice.Imbalanced mechanistic target of rapamycin C1 and C2 activity in the cerebellum of Angelman syndrome mice impairs motor function.Guidelines for visualizing and annotating rule-based models The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation.Target of rapamycin (TOR) in nutrient signaling and growth control RSK regulates activated BRAF signalling to mTORC1 and promotes melanoma growth Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cells.Overview of the Cancer Genetics and Pathway Curation tasks of BioNLP Shared Task 2013.CARFMAP: A Curated Pathway Map of Cardiac Fibroblasts.

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A comprehensive map of the mTOR signaling network.

http://www.wikidata.org/entity/Q37823206

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on December 2010

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

A comprehensive map of the mTOR signaling network.

@en

A comprehensive map of the mTOR signaling network.

@nl

type

label

A comprehensive map of the mTOR signaling network.

@en

A comprehensive map of the mTOR signaling network.

@nl

prefLabel

A comprehensive map of the mTOR signaling network.

@en

A comprehensive map of the mTOR signaling network.

@nl

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Molecular Systems Biology

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A comprehensive map of the mTOR signaling network.

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Etienne Caron

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Hiroaki Kitano

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Marc Therrien

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Samik Ghosh

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Yukiko Matsuoka

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

P2860

The public road to high-quality curated biological pathways

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

Human Sin1 contains Ras-binding and pleckstrin homology domains and suppresses Ras signalling

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

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10.1038/MSB.2010.108

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6

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Dariel Ashton-Beaucage

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Claude Perreault

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2010-12-01T00:00:00Z

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2010-12-21T00:00:00Z

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biomedical investigative technique

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3018167

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