Mechanisms that promote and suppress chromosomal translocations in lymphocytes.
about
Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)Breaking bad: R-loops and genome integrityTranscriptional stalling in B-lymphocytes: a mechanism for antibody diversification and maintenance of genomic integrityRelated Mechanisms of Antibody Somatic Hypermutation and Class Switch RecombinationDNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choiceThe response to and repair of RAG-mediated DNA double-strand breaksHomology and enzymatic requirements of microhomology-dependent alternative end joiningRole of non-homologous end joining in V(D)J recombinationThe CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myelomaChromosomal translocations and karyotype complexity in chronic lymphocytic leukemia: a systematic reappraisal of classic cytogenetic data.DNA double-strand break repair in Penaeus monodon is predominantly dependent on homologous recombination.Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.Mobile elements and viral integrations prompt considerations for bacterial DNA integration as a novel carcinogenIdentification of chromosomal translocation hotspots via scan statisticsMechanisms that can promote peripheral B-cell lymphoma in ATM-deficient mice.Cernunnos influences human immunoglobulin class switch recombination and may be associated with B cell lymphomagenesisThe DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombinationRoles for histone H3K4 methyltransferase activities during immunoglobulin class-switch recombinationInter- and intratumoral heterogeneity of BCL2 correlates with IgH expression and prognosis in follicular lymphoma.Genomic hallmarks of genes involved in chromosomal translocations in hematological cancer.RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycleBridge-induced chromosome translocation in yeast relies upon a Rad54/Rdh54-dependent, Pol32-independent pathwayThe AID-induced DNA damage response in chromatin.HCoDES reveals chromosomal DNA end structures with single-nucleotide resolutionFate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development.Yeast pol4 promotes tel1-regulated chromosomal translocations.Dynamics of double strand breaks and chromosomal translocationsFunctional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair.Spatial organization of the mouse genome and its role in recurrent chromosomal translocationsRAG Represents a Widespread Threat to the Lymphocyte Genome.Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.Oncogenic Myc translocations are independent of chromosomal location and orientation of the immunoglobulin heavy chain locusMicrohomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesionsc-Myc suppression of DNA double-strand break repair.Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching.Close proximity to Igh is a contributing factor to AID-mediated translocations.Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas.Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system.Identification of early replicating fragile sites that contribute to genome instability53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma.
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Mechanisms that promote and suppress chromosomal translocations in lymphocytes.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2011
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mechanisms that promote and suppress chromosomal translocations in lymphocytes.
@en
Mechanisms that promote and suppress chromosomal translocations in lymphocytes.
@nl
type
label
Mechanisms that promote and suppress chromosomal translocations in lymphocytes.
@en
Mechanisms that promote and suppress chromosomal translocations in lymphocytes.
@nl
prefLabel
Mechanisms that promote and suppress chromosomal translocations in lymphocytes.
@en
Mechanisms that promote and suppress chromosomal translocations in lymphocytes.
@nl
P2093
P1476
Mechanisms that promote and suppress chromosomal translocations in lymphocytes.
@en
P2093
Frederick W Alt
Monica Gostissa
Roberto Chiarle
P304
P356
10.1146/ANNUREV-IMMUNOL-031210-101329
P577
2011-01-01T00:00:00Z