about
Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stressGenome-wide association study of alcohol dependenceGenome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumptionBrain activation induced by voluntary alcohol and saccharin drinking in rats assessed with manganese-enhanced magnetic resonance imaging.Gene discovery in neuropharmacological and behavioral studies using Affymetrix microarray data.Modulation of nucleus accumbens connectivity by alcohol drinking and naltrexone in alcohol-preferring rats: A manganese-enhanced magnetic resonance imaging study.Suppressed neuropeptide Y (NPY) mRNA in rat amygdala following restraint stress.Translating the neuroscience of alcoholism into clinical treatments: from blocking the buzz to curing the blues.Ethanol-induced activation of AKT and DARPP-32 in the mouse striatum mediated by opioid receptors.Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect.Glycine transporter-1 blockade leads to persistently reduced relapse-like alcohol drinking in rats.Functional NPY variation as a factor in stress resilience and alcohol consumption in rhesus macaques.Coordinated dysregulation of mRNAs and microRNAs in the rat medial prefrontal cortex following a history of alcohol dependenceXRCC5 as a risk gene for alcohol dependence: evidence from a genome-wide gene-set-based analysis and follow-up studies in Drosophila and humans.Dopamine systems adaptation during acquisition and consolidation of a skill.Increased mRNA Levels of TCF7L2 and MYC of the Wnt Pathway in Tg-ArcSwe Mice and Alzheimer's Disease Brain.Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor systemLong-lasting tolerance to alcohol following a history of dependence.Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat.Expression Profiling in Alcoholism Research.Pharmacological consequence of the A118G μ opioid receptor polymorphism on morphine- and fentanyl-mediated modulation of Ca²⁺ channels in humanized mouse sensory neurons.mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts.Functional genomics strategies to identify susceptibility genes and treatment targets in alcohol dependence.The search for candidate genes of alcoholism: evidence from expression profiling studies.RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release.The Calpain Inhibitor A-705253 Attenuates Alcohol-Seeking and Relapse with Low Side-Effect Profile.The alcohol-preferring AA and alcohol-avoiding ANA rats: neurobiology of the regulation of alcohol drinking.Convergent evidence from alcohol-dependent humans and rats for a hyperdopaminergic state in protracted abstinence.Long-term suppression of forebrain neurogenesis and loss of neuronal progenitor cells following prolonged alcohol dependence in rats.Association of Protein Phosphatase PPM1G With Alcohol Use Disorder and Brain Activity During Behavioral Control in a Genome-Wide Methylation Analysis.Neuroplasticity in brain reward circuitry following a history of ethanol dependence.Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence.Targeting brain angiotensin and corticotrophin-releasing hormone systems interaction for the treatment of mood and alcohol use disorders.Acute ethanol challenge inhibits glycogen synthase kinase-3beta in the rat prefrontal cortexβ-Arrestin 2 knockout mice exhibit sensitized dopamine release and increased reward in response to a low dose of alcohol.Functional CRH variation increases stress-induced alcohol consumption in primates.Genetic variation and brain gene expression in rodent models of alcoholism implications for medication development.An integrated genome research network for studying the genetics of alcohol addiction.Postdependent state in rats as a model for medication development in alcoholism.Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis
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P50
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hulumtues
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Wolfgang H Sommer
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Wolfgang H Sommer
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Wolfgang H Sommer
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