about
Hyperlipidemia, tissue factor, coagulation, and simvastatinPF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI.Eculizumab therapy results in rapid and sustained decreases in markers of thrombin generation and inflammation in patients with PNH independent of its effects on hemolysis and microparticle formation.Platelet ITAM signaling is critical for vascular integrity in inflammation.Roles of PAR1 and PAR2 in viral myocarditis.Regulation of tissue factor gene expression in monocytes and endothelial cells: Thromboxane A2 as a new playerProtease-activated receptor 2 deficiency reduces cardiac ischemia/reperfusion injury.Role of fibrinogen and protease-activated receptors in acute xenobiotic-induced cholestatic liver injury.Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated miceThe septic milieu triggers expression of spliced tissue factor mRNA in human platelets.Role of tissue factor in venous thrombosis.Protease activated receptor-2 contributes to heart failure.Protease-activated receptors and myocardial infarctionMicroparticles in hemostasis and thrombosis.Protease-activated receptor 1 and hematopoietic cell tissue factor are required for hepatic steatosis in mice fed a Western diet.Pre-analytical and analytical variables affecting the measurement of plasma-derived microparticle tissue factor activity.Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo.Myeloid cell tissue factor does not contribute to venous thrombogenesis in an electrolytic injury model.Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell diseaseCirculating microparticle tissue factor activity is increased in patients with cirrhosisTissue factor-positive tumor microvesicles activate platelets and enhance thrombosis in mice.PAR-1 contributes to the innate immune response during viral infection.Hepatocyte tissue factor activates the coagulation cascade in miceLow levels of tissue factor are compatible with development and hemostasis in mice.Coagulation, protease-activated receptors, and viral myocarditis.Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations.Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease.Alternatively spliced tissue factor and full-length tissue factor protect cardiomyocytes against TNF-α-induced apoptosis.Multiple roles of the coagulation protease cascade during virus infection.Tissue factor and its measurement in whole blood, plasma, and microparticles.Tissue factor in health and disease.Sources of tissue factor that contribute to thrombosis after rupture of an atherosclerotic plaque.Role of tissue factor in atherothrombosis.Prothrombotic mechanisms and anticoagulant therapy in dogs with immune-mediated hemolytic anemia.Microvesicles as risk markers for venous thrombosis.The antithrombotic effects of statins.Protease-Activated Receptor 1 Enhances Poly I:C Induction of the Antiviral Response in Macrophages and Mice.Contributions of thrombin targets to tissue factor-dependent metastasis in hyperthrombotic mice.Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis.Regulation of thrombin-induced plasminogen activator inhibitor-1 in 4T1 murine breast cancer cells.
P50
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Nigel Mackman
@ast
Nigel Mackman
@en
Nigel Mackman
@es
Nigel Mackman
@nl
Nigel Mackman
@sl
type
label
Nigel Mackman
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Nigel Mackman
@en
Nigel Mackman
@es
Nigel Mackman
@nl
Nigel Mackman
@sl
prefLabel
Nigel Mackman
@ast
Nigel Mackman
@en
Nigel Mackman
@es
Nigel Mackman
@nl
Nigel Mackman
@sl
P106
P21
P31
P496
0000-0002-9170-7700