about
Identification and expression of genes involved in biosynthesis of L-oleandrose and its intermediate L-olivose in the oleandomycin producer Streptomyces antibioticusFunctional analysis of OleY L-oleandrosyl 3-O-methyltransferase of the oleandomycin biosynthetic pathway in Streptomyces antibioticusBiosynthesis of the RNA polymerase inhibitor streptolydigin in Streptomyces lydicus: tailoring modification of 3-methyl-aspartateNovel compounds produced by Streptomyces lydicus NRRL 2433 engineered mutants altered in the biosynthesis of streptolydigin.Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycinCharacterization and engineering of the biosynthesis gene cluster for antitumor macrolides PM100117 and PM100118 from a marine actinobacteria: generation of a novel improved derivativeStreptomyces antibioticus contains at least three oleandomycin-resistance determinants, one of which shows similarity with proteins of the ABC-transporter superfamily.Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering.Antitumor compounds from actinomycetes: from gene clusters to new derivatives by combinatorial biosynthesis.Post-PKS tailoring steps in natural product-producing actinomycetes from the perspective of combinatorial biosynthesis.Hutchinson's legacy: keeping on polyketide biosynthesis.Molecular insights on the biosynthesis of antitumour compounds by actinomycetes.A second ABC transporter is involved in oleandomycin resistance and its secretion by Streptomyces antibioticus.The dnrO gene encodes a DNA-binding protein that regulates daunorubicin production in Streptomyces peucetius by controlling expression of the dnrN pseudo response regulator gene.Engineered jadomycin analogues with altered sugar moieties revealing JadS as a substrate flexible O-glycosyltransferase.Elucidation of the glycosylation steps during biosynthesis of antitumor macrolides PM100117 and PM100118 and engineering for novel derivatives.Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074.Genome Mining of Streptomyces sp. Tü 6176: Characterization of the Nataxazole Biosynthesis Pathway.New insights into paulomycin biosynthesis pathway in Streptomyces albus J1074 and generation of novel derivatives by combinatorial biosynthesis.Glycosylated derivatives of steffimycin: insights into the role of the sugar moieties for the biological activity.Separation of anti-angiogenic and cytotoxic activities of borrelidin by modification at the C17 side chain.Biosynthesis of the angiogenesis inhibitor borrelidin: directed biosynthesis of novel analogues.Caboxamycin biosynthesis pathway and identification of novel benzoxazoles produced by cross-talk in Streptomyces sp. NTK 937Exploring the biocombinatorial potential of benzoxazoles: generation of novel caboxamycin derivatives.Participation of putative glycoside hydrolases SlgC1 and SlgC2 in the biosynthesis of streptolydigin in Streptomyces lydicus.Identification by Genome Mining of a Type I Polyketide Gene Cluster from Streptomyces argillaceus Involved in the Biosynthesis of Pyridine and Piperidine Alkaloids Argimycins P.Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus.A cytochrome P450-like gene possibly involved in oleandomycin biosynthesis by Streptomyces antibioticus.Draft Genome Sequence of Marine Actinomycete Streptomyces sp. Strain NTK 937, Producer of the Benzoxazole Antibiotic CaboxamycinAmino acid precursor supply in the biosynthesis of the RNA polymerase inhibitor streptolydigin by Streptomyces lydicus.Modulation of deoxysugar transfer by the elloramycin glycosyltransferase ElmGT through site-directed mutagenesis.Chapter 11. Sugar biosynthesis and modification.Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tü4055: insights into nitrile formation.Analysis of a Streptomyces antibioticus chromosomal region involved in oleandomycin biosynthesis, which encodes two glycosyltransferases responsible for glycosylation of the macrolactone ring.Characterization of a Streptomyces antibioticus gene cluster encoding a glycosyltransferase involved in oleandomycin inactivation.Novel Bioactive Paulomycin Derivatives Produced by Streptomyces albus J1074.Searching for Glycosylated Natural Products in Actinomycetes and Identification of Novel Macrolactams and Angucyclines.Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase.New Insights into the Biosynthesis Pathway of Polyketide Alkaloid Argimycins P in Streptomyces argillaceus.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Carlos Olano
@ast
Carlos Olano
@en
Carlos Olano
@es
Carlos Olano
@nl
Carlos Olano
@sl
type
label
Carlos Olano
@ast
Carlos Olano
@en
Carlos Olano
@es
Carlos Olano
@nl
Carlos Olano
@sl
prefLabel
Carlos Olano
@ast
Carlos Olano
@en
Carlos Olano
@es
Carlos Olano
@nl
Carlos Olano
@sl
P1053
P-4647-2016
P106
P1153
35618968000
P21
P2798
P31
P3829
P496
0000-0001-5440-3540