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Na(+)/H(+) exchanger 1 directly binds to calcineurin A and activates downstream NFAT signaling, leading to cardiomyocyte hypertrophyTransient receptor potential (TRP) channels and cardiac fibrosis"TRP inflammation" relationship in cardiovascular systemSignificant roles of anti-aging protein klotho and fibroblast growth factor23 in cardiovascular diseaseSignaling effectors underlying pathologic growth and remodeling of the heartHeart failure with preserved ejection fraction: mechanisms, clinical features, and therapiesPPARα activation inhibits endothelin-1-induced cardiomyocyte hypertrophy by prevention of NFATc4 binding to GATA-4Recapitulating maladaptive, multiscale remodeling of failing myocardium on a chip.Hypertrophic scar contracture is mediated by the TRPC3 mechanical force transducer via NFkB activation.Transient receptor potential (TRP) channels: a clinical perspectiveBiomechanics of cardiac electromechanical coupling and mechanoelectric feedback.Compensatory and decompensatory alterations in cardiomyocyte Ca2+ dynamics in hearts with diastolic dysfunction following aortic banding.Etanercept protects rat cardiomyocytes against hypertrophy by regulating inflammatory cytokines secretion and cell apoptosisCalcineurin and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusionFGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy.Transient receptor potential channels contribute to pathological structural and functional remodeling after myocardial infarctionRoles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis.TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1.Reducing endoglin activity limits calcineurin and TRPC-6 expression and improves survival in a mouse model of right ventricular pressure overload.Role of TRP channels in the cardiovascular system.Store-operated calcium entry and the localization of STIM1 and Orai1 proteins in isolated mouse sinoatrial node cells.The involvement of TRPC3 channels in sinoatrial arrhythmiasA cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptideThe sperm surface localization of the TRP-3/SPE-41 Ca2+ -permeable channel depends on SPE-38 function in Caenorhabditis elegans.mTOR signaling in mice with dysfunctional cardiac ryanodine receptor ion channel.Activation of transient receptor potential canonical 3 (TRPC3)-mediated Ca2+ entry by A1 adenosine receptor in cardiomyocytes disturbs atrioventricular conductionTRPC4α and TRPC4β Similarly Affect Neonatal Cardiomyocyte Survival during Chronic GPCR Stimulation.Activation of TRPV1 attenuates high salt-induced cardiac hypertrophy through improvement of mitochondrial functionAirway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migrationStore-operated Ca2+ entry supports contractile function in hearts of hibernators.A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo.Regulation of transport in the connecting tubule and cortical collecting ductCardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart.Cardiac Stim1 Silencing Impairs Adaptive Hypertrophy and Promotes Heart Failure Through Inactivation of mTORC2/Akt Signaling.Axial stretch-dependent cation entry in dystrophic cardiomyopathy: Involvement of several TRPs channelsOld dog, new tricks: novel cardiac targets and stress regulation by protein kinase G.STIM1/Orai1-mediated SOCE: current perspectives and potential roles in cardiac function and pathologyCombined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria.STIM/Orai signalling complexes in vascular smooth muscle.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
TRPC channels as effectors of cardiac hypertrophy.
@en
TRPC channels as effectors of cardiac hypertrophy.
@nl
type
label
TRPC channels as effectors of cardiac hypertrophy.
@en
TRPC channels as effectors of cardiac hypertrophy.
@nl
prefLabel
TRPC channels as effectors of cardiac hypertrophy.
@en
TRPC channels as effectors of cardiac hypertrophy.
@nl
P1433
P1476
TRPC channels as effectors of cardiac hypertrophy.
@en
P2093
Petra Eder
P304
P356
10.1161/CIRCRESAHA.110.225888
P577
2011-01-01T00:00:00Z