Hyaluronan metabolism in remodeling extracellular matrix: probes for imaging and therapy of breast cancer.
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Collagen VI and hyaluronan: the common role in breast cancerAmine-modified hyaluronic acid-functionalized porous silicon nanoparticles for targeting breast cancer tumors.Cellular heterogeneity profiling by hyaluronan probes reveals an invasive but slow-growing breast tumor subset.A RHAMM mimetic peptide blocks hyaluronan signaling and reduces inflammation and fibrogenesis in excisional skin wounds.Intracellular Survival of Leishmania major Depends on Uptake and Degradation of Extracellular Matrix Glycosaminoglycans by Macrophages.Identification, design and synthesis of tubulin-derived peptides as novel hyaluronan mimetic ligands for the receptor for hyaluronan-mediated motility (RHAMM/HMMR).Uncovering the dual role of RHAMM as an HA receptor and a regulator of CD44 expression in RHAMM-expressing mesenchymal progenitor cells.Imaging of homeostatic, neoplastic, and injured tissues by HA-based probes.Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation.Tissue engineering concept in the research of the tumor biology.Deregulation of hyaluronan synthesis, degradation and binding promotes breast cancer.Therapeutic targeting of hyaluronan in the tumor stroma.Hyaluronan and RHAMM in wound repair and the "cancerization" of stromal tissues.Hyaluronan differently modulates TLR-4 and the inflammatory response in mouse chondrocytes.Porous chitosan-hyaluronic acid scaffolds as a mimic of glioblastoma microenvironment ECM.Characterization of the Tumor Microenvironment and Tumor-Stroma Interaction by Non-invasive Preclinical ImagingCD44-specific supramolecular hydrogels for fluorescence molecular imaging of stem-like gastric cancer cells.The inhibition of hyaluronan degradation reduced pro-inflammatory cytokines in mouse synovial fibroblasts subjected to collagen-induced arthritis.Human hyaluronic acid synthase-1 promotes malignant transformation via epithelial-to-mesenchymal transition, micronucleation and centrosome abnormalities.Expression-based analyses indicate a central role for hypoxia in driving tumor plasticity through microenvironment remodeling and chromosomal instability
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P2860
Hyaluronan metabolism in remodeling extracellular matrix: probes for imaging and therapy of breast cancer.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 January 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hyaluronan metabolism in remod ...... and therapy of breast cancer.
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Hyaluronan metabolism in remod ...... and therapy of breast cancer.
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type
label
Hyaluronan metabolism in remod ...... and therapy of breast cancer.
@en
Hyaluronan metabolism in remod ...... and therapy of breast cancer.
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prefLabel
Hyaluronan metabolism in remod ...... and therapy of breast cancer.
@en
Hyaluronan metabolism in remod ...... and therapy of breast cancer.
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P2860
P356
P1433
P1476
Hyaluronan metabolism in remod ...... and therapy of breast cancer.
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P2093
P2860
P304
P356
10.1039/C0IB00096E
P577
2011-01-24T00:00:00Z