about
The Arp2/3 activator WASH regulates α5β1-integrin-mediated invasive migrationWASP family proteins: their evolution and its physiological implications.Gdt2 regulates the transition of Dictyostelium cells from growth to differentiationParasexual genetics of Dictyostelium gene disruptions: identification of a ras pathway using diploidsThe Dictyostelium genome: the private life of a social model revealed?p21-Activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophilsAn improved chamber for direct visualisation of chemotaxisMelanoma cells break down LPA to establish local gradients that drive chemotactic dispersalPseudopod growth and evolution during cell movement is controlled through SCAR/WAVE dephosphorylation.Self-Generated Chemoattractant Gradients: Attractant Depletion Extends the Range and Robustness of ChemotaxisScar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complexPIP3, PIP2, and cell movement--similar messages, different meanings?Inference of the drivers of collective movement in two cell types: Dictyostelium and melanomaRacG regulates morphology, phagocytosis, and chemotaxisEntamoeba histolytica cell movement: a central role for self-generated chemokines and chemorepellentsLoss of Dictyostelium HSPC300 causes a scar-like phenotype and loss of SCAR protein.SCAR/WAVE is activated at mitosis and drives myosin-independent cytokinesisThe induction of autophagy by mechanical stress.Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression.N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods.SCAR knockouts in Dictyostelium: WASP assumes SCAR's position and upstream regulators in pseudopodsAbi is required for modulation and stability but not localization or activation of the SCAR/WAVE complexPhosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence.PIP₃-dependent macropinocytosis is incompatible with chemotaxisScar/WAVE3 contributes to motility and plasticity of lamellipodial dynamics but not invasion in three dimensions.A plasma membrane template for macropinocytic cups.Replacement of the essential Dictyostelium Arp2 gene by its Entamoeba homologue using parasexual genetics.Dynamics of the Dictyostelium Arp2/3 complex in endocytosis, cytokinesis, and chemotaxis.Dictyostelium: an ideal organism for genetic dissection of Ras signalling networks.Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast.Two cAMP receptors activate common signaling pathways in Dictyostelium.Overflow in science and its implications for trust.WASP and SCAR/WAVE proteins: the drivers of actin assemblyActin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis.Comparative genome and transcriptome analyses of the social amoeba Acytostelium subglobosum that accomplishes multicellular development without germ-soma differentiation.Impaired neutrophil directional chemotactic accuracy in chronic periodontitis patients.Protein conformation: through a lens, darkly.Regulation of WASP: PIP2 Pipped by Toca-1?Regulation of actin assembly by SCAR/WAVE proteins.Phosphorylation of actin-related protein 2 (Arp2) is required for normal development and cAMP chemotaxis in Dictyostelium.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Robert H Insall
@ast
Robert H Insall
@en
Robert H Insall
@es
Robert H Insall
@nl
Robert H Insall
@sl
type
label
Robert H Insall
@ast
Robert H Insall
@en
Robert H Insall
@es
Robert H Insall
@nl
Robert H Insall
@sl
prefLabel
Robert H Insall
@ast
Robert H Insall
@en
Robert H Insall
@es
Robert H Insall
@nl
Robert H Insall
@sl
P108
P1053
G-5611-2011
P106
P108
P21
P31
P3829
P496
0000-0003-4898-040X