Bioanalytical LC-MS of therapeutic oligonucleotides.

Bioanalytical LC-MS of therapeutic oligonucleotides.

Item
http://www.wikidata.org/entity/Q37851144
Phosphorothioate oligonucleotide quantification by μ-liquid chromatography-mass spectrometry.Mass spectrometry of modified RNAs: recent developmentsLC-MS of oligonucleotides: applications in biomedical research.Advances in quantitative bioanalysis of oligonucleotide biomarkers and therapeutics.Pharmacokinetics and Pharmacodynamics of a 13-mer LNA-inhibitor-miR-221 in Mice and Non-human Primates.Systematic optimization of ion-pairing agents and hexafluoroisopropanol for enhanced electrospray ionization mass spectrometry of oligonucleotides.Desulfurization of phosphorothioate oligonucleotides via the sulfur-by-oxygen replacement induced by the hydroxyl radical during negative electrospray ionization mass spectrometry.Characterization of Byproducts from Chemical Syntheses of Oligonucleotides Containing 1-Methyladenine and 3-Methylcytosine.Quantitative analysis of imetelstat in plasma with LC-MS/MS using solid-phase or hybridization extraction.Quantification of oligonucleotides by LC-MS/MS: the challenges of quantifying a phosphorothioate oligonucleotide and multiple metabolites.Preliminary investigation into the use of a real-time PCR method for the quantification of an oligonucleotide in human plasma and the development of novel acceptance criteria.Regulated bioanalysis of oligonucleotide therapeutics and biomarkers: qPCR versus chromatographic assays.Quantitative determination of a siRNA (AD00370) in rat plasma using peptide nucleic acid probe and HPLC with fluorescence detection.
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Bioanalytical LC-MS of therapeutic oligonucleotides.

Item
http://www.wikidata.org/entity/Q37851144
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Bioanalytical LC-MS of therapeutic oligonucleotides.
@en
Bioanalytical LC-MS of therapeutic oligonucleotides.
@nl
type
label
Bioanalytical LC-MS of therapeutic oligonucleotides.
@en
Bioanalytical LC-MS of therapeutic oligonucleotides.
@nl
prefLabel
Bioanalytical LC-MS of therapeutic oligonucleotides.
@en
Bioanalytical LC-MS of therapeutic oligonucleotides.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P356
P1433
P1476
Bioanalytical LC-MS of therapeutic oligonucleotides.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698