Strategies for the design of RNA-binding small molecules.
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5'-UTR RNA G-quadruplexes: translation regulation and targetingRecent Advances in Developing Small Molecules Targeting Nucleic AcidAmetantrone-based compounds as potential regulators of Tau pre-mRNA alternative splicing.Binding characteristics of small molecules that mimic nucleocapsid protein-induced maturation of stem-loop 1 of HIV-1 RNA.Efficient in silico exploration of RNA interhelical conformations using Euler angles and WExploreAdvances in targeting nucleocapsid-nucleic acid interactions in HIV-1 therapy.Targeting folded RNA: a branched peptide boronic acid that binds to a large surface area of HIV-1 RRE RNALigandRNA: computational predictor of RNA-ligand interactions.Discovery of the first small-molecule CsrA-RNA interaction inhibitors using biophysical screening technologies.Small Molecule-Based Pattern Recognition To Classify RNA Structure.Applying a high-throughput fluorescence polarization assay for the discovery of chemical probes blocking La:RNA interactions in vitro and in cells.6-desfluoroquinolones as HIV-1 Tat-mediated transcription inhibitors.Binding-interaction prediction of RNA-binding ligands.Conceptual approaches for lncRNA drug discovery and future strategies.Uptake and localisation of small-molecule fluorescent probes in living cells: a critical appraisal of QSAR models and a case study concerning probes for DNA and RNA.Mapping the interactions of selected antibiotics and their Cu2+ complexes with the antigenomic δ ribozyme.Development of pharmacophore models for small molecules targeting RNA: Application to the RNA repeat expansion in myotonic dystrophy type 1.SMMRNA: a database of small molecule modulators of RNA.Recent advances in the identification of Tat-mediated transactivation inhibitors: progressing toward a functional cure of HIV.Synthetic RNA recognition motifs that selectively recognize HIV-1 trans-activation response element hairpin RNA.Binding thermodynamics of paromomycin, neomycin, neomycin-dinucleotide and -diPNA conjugates to bacterial and human rRNA.The development of peptide ligands that target helix 69 rRNA of bacterial ribosomes.Local RNA flexibility perturbation of the IRES element induced by a novel ligand inhibits viral RNA translation.Conformational readout of RNA by small ligandsThermodynamic studies of a series of homologous HIV-1 TAR RNA ligands reveal that loose binders are stronger Tat competitors than tight ones.Discovery of Key Physicochemical, Structural, and Spatial Properties of RNA-Targeted Bioactive Ligands.Exploring the impact of the side-chain length on peptide/RNA binding events.Probe the Binding Mode of Aristololactam-β-D-glucoside to Phenylalanine Transfer RNAin SilicoExploring the effect of aminoglycoside guanidinylation on ligands for Tau exon 10 splicing regulatory element RNAIdentification of Ligands for the Tau Exon 10 Splicing Regulatory Element RNA by Using Dynamic Combinatorial Chemistry
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Strategies for the design of RNA-binding small molecules.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2010
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Strategies for the design of RNA-binding small molecules.
@en
Strategies for the design of RNA-binding small molecules.
@nl
type
label
Strategies for the design of RNA-binding small molecules.
@en
Strategies for the design of RNA-binding small molecules.
@nl
prefLabel
Strategies for the design of RNA-binding small molecules.
@en
Strategies for the design of RNA-binding small molecules.
@nl
P2860
P356
P1476
Strategies for the design of RNA-binding small molecules.
@en
P2093
Fareed Aboul-ela
P2860
P304
P356
10.4155/FMC.09.149
P577
2010-01-01T00:00:00Z