about
Notch signaling: its roles and therapeutic potential in hematological malignanciesProteins and small molecules for cellular regenerative medicineHematopoietic stem cell niche maintenance during homeostasis and regenerationWnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia developmentParathyroid hormone administration improves bone marrow microenvironment and partially rescues haematopoietic defects in Bmi1-null miceIdentification of renin progenitors in the mouse bone marrow that give rise to B-cell leukaemia.Comparative and evolutionary analysis of the HES/HEY gene family reveal exon/intron loss and teleost specific duplication events.Notch signaling in the malignant bone marrow microenvironment: implications for a niche-based model of oncogenesis.Notch Stimulates Both Self-Renewal and Lineage Plasticity in a Subset of Murine CD9High Committed Megakaryocytic Progenitors.Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment.Role of LRF/Pokemon in lineage fate decisions.Pleiotropic Functions of H3K27Me3 Demethylases in Immune Cell Differentiation.Multiple allogeneic progenitors in combination function as a unit to support early transient hematopoiesis in transplantation.Cancer stem cells and therapeutic targets: an emerging field for cancer treatmentIdentification of microRNA-regulated pathways using an integration of microRNA-mRNA microarray and bioinformatics analysis in CD34+ cells of myelodysplastic syndromes.Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia.Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation.Myeloproliferation and hematopoietic stem cell dysfunction due to defective Notch receptor modification by O-fucose glycans.Roles of p53 in various biological aspects of hematopoietic stem cells.Differential requirements for Wnt and Notch signaling in hematopoietic versus thymic niches.The functional relationship between hematopoietic stem cells and developing T lymphocytes.A red-shifted fluorescent substrate for aldehyde dehydrogenase.Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency.A small-molecule/cytokine combination enhances hematopoietic stem cell proliferation via inhibition of cell differentiation.Endothelium-targeted human Delta-like 1 enhances the regeneration and homing of human cord blood stem and progenitor cells.Notch cooperates with Lozenge/Runx to lock haemocytes into a differentiation programme.SALL4 as a transcriptional and epigenetic regulator in normal and leukemic hematopoiesis.γ-Secretase inhibitor reverts the Notch signaling attenuation of osteogenic differentiation in aged bone marrow mesenchymal stem cells.Cell intrinsic regulation of external hematopoietic stem cell stress.
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P2860
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 07 June 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Notch signaling in mammalian hematopoietic stem cells.
@en
Notch signaling in mammalian hematopoietic stem cells.
@nl
type
label
Notch signaling in mammalian hematopoietic stem cells.
@en
Notch signaling in mammalian hematopoietic stem cells.
@nl
prefLabel
Notch signaling in mammalian hematopoietic stem cells.
@en
Notch signaling in mammalian hematopoietic stem cells.
@nl
P2093
P2860
P356
P1433
P1476
Notch signaling in mammalian hematopoietic stem cells.
@en
P2093
P2860
P2888
P304
P356
10.1038/LEU.2011.127
P577
2011-06-07T00:00:00Z