Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors.
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Lyn is involved in CD24-induced ERK1/2 activation in colorectal cancerSelective Sensing of Tyrosine Phosphorylation in Peptides Using Terbium(III) ComplexesFinding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging MoleculesThe molecular rationale of Src inhibition in colorectal carcinomasTrespassing cancer cells: 'fingerprinting' invasive protrusions reveals metastatic culpritsLarge granular lymphocytosis during dasatinib therapyLipid biology of breast cancerA membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cellsDiscovery of Diverse Small-Molecule Inhibitors of Mammalian Sterile20-like Kinase 3 (MST3)Radotinib Induces Apoptosis of CD11b+ Cells Differentiated from Acute Myeloid Leukemia Cellsβ3 integrin in cardiac fibroblast is critical for extracellular matrix accumulation during pressure overload hypertrophy in mouseDasatinib synergises with irinotecan to suppress hepatocellular carcinoma via inhibiting the protein synthesis of PLK1.Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells.C-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics.Bosutinib reduces the efficacy of Dasatinib in triple-negative breast cancer cell lines.The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.Src inhibitors in the treatment of metastatic bone disease: rationale and clinical dataThe protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells.Dasatinib worsens the effect of cetuximab in combination with fractionated radiotherapy in FaDu- and A431-derived xenografted tumoursThe ETS family of oncogenic transcription factors in solid tumours.Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancerMutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy.iPhos: a toolkit to streamline the alkaline phosphatase-assisted comprehensive LC-MS phosphoproteome investigation.SRC drives growth of antiestrogen resistant breast cancer cell lines and is a marker for reduced benefit of tamoxifen treatmentLYN-activating mutations mediate antiestrogen resistance in estrogen receptor-positive breast cancerLoss of Androgen-Regulated MicroRNA 1 Activates SRC and Promotes Prostate Cancer Bone Metastasis.The importance of Src signaling in sarcoma.Phase II studies of two different schedules of dasatinib in bone metastasis predominant metastatic breast cancer: SWOG S0622Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells.Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-ASActive efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.Dasatinib synergizes with both cytotoxic and signal transduction inhibitors in heterogeneous breast cancer cell lines--lessons for design of combination targeted therapyDasatinib inhibits TGFβ-induced myofibroblast differentiation through Src-SRF Pathway.Acquired resistance to 5-fluorouracil via HSP90/Src-mediated increase in thymidylate synthase expression in colon cancer.Characterization of a mantle cell lymphoma cell line resistant to the Chk1 inhibitor PF-00477736Inhibition of Lyn is a promising treatment for mantle cell lymphoma with bortezomib resistance.Activation of Src, Fyn and Yes non-receptor tyrosine kinases in keratinocytes expressing human papillomavirus (HPV) type 16 E7 oncoprotein.Identification and functional characterization of p130Cas as a substrate of protein tyrosine phosphatase nonreceptor 14The small GTPase ADP-Ribosylation Factor 1 mediates the sensitivity of triple negative breast cancer cells to EGFR tyrosine kinase inhibitors.Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma.
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P2860
Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 13 June 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Inhibition of SRC family kinas ...... combinations in solid tumors.
@en
Inhibition of SRC family kinas ...... combinations in solid tumors.
@nl
type
label
Inhibition of SRC family kinas ...... combinations in solid tumors.
@en
Inhibition of SRC family kinas ...... combinations in solid tumors.
@nl
prefLabel
Inhibition of SRC family kinas ...... combinations in solid tumors.
@en
Inhibition of SRC family kinas ...... combinations in solid tumors.
@nl
P1476
Inhibition of SRC family kinas ...... e combinations in solid tumors
@en
P2093
Atanasio Pandiella
Samuel Seoane
P304
P356
10.1158/1078-0432.CCR-10-2616
P407
P577
2011-06-13T00:00:00Z