Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation.
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Immune Checkpoint Inhibitors and Prostate Cancer: A New Frontier?Immunotherapy for cancer in the central nervous system: Current and future directionsNarrowing the Gap: Preserving Repertoire Diversity Despite Clonal Selection during the CD4 T Cell ResponseCo-Stimulatory Blockade of the CD28/CD80-86/CTLA-4 Balance in Transplantation: Impact on Memory T Cells?Genetic engineering with T cell receptorsForsythoside A Inhibits BVDV Replication via TRAF2-Dependent CD28–4-1BB Signaling in Bovine PBMCsAutosomal dominant immune dysregulation syndrome in humans with CTLA4 mutationsEarly-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4T cell costimulatory and coinhibitory pathways in vascular inflammatory diseasesHuman mesenchymal stromal cells from adult and neonatal sources: a comparative in vitro analysis of their immunosuppressive properties against T cells.Cancer immunotherapy by targeting immune checkpoints: mechanism of T cell dysfunction in cancer immunity and new therapeutic targets.Targeting regulatory T cells to improve vaccine immunogenicity in early life.Immune suppression in cynomolgus monkeys by XPro9523: an improved CTLA4-Ig fusion with enhanced binding to CD80, CD86 and neonatal Fc receptor FcRnMurine CD4⁺CD25⁻ cells activated in vitro with PMA/ionomycin and anti-CD3 acquire regulatory function and ameliorate experimental colitis in vivoThe soluble isoform of CTLA-4 as a regulator of T-cell responses.mTOR signaling, Tregs and immune modulation.Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming.Ctla-4 modulates the differentiation of inducible Foxp3+ Treg cells but IL-10 mediates their function in experimental autoimmune encephalomyelitis.Regulatory T cells require TCR signaling for their suppressive functionBeyond adjuvants: immunomodulation strategies to enhance T cell immunityConstitutive clathrin-mediated endocytosis of CTLA-4 persists during T cell activation.CD4+ FOXP3+ Regulatory T Cells Exhibit Impaired Ability to Suppress Effector T Cell Proliferation in Patients with Turner Syndrome.A transendocytosis model of CTLA-4 function predicts its suppressive behavior on regulatory T cells.Characterization of Regulatory T-Cell Markers in CD4+ T Cells of the Upper Airway MucosaThe molecular mechanisms of regulatory T cell immunosuppressionRecent developments on immunotherapy for brain cancer.Dead on arrival: understanding the failure of CTLA4-immunoglobulin therapy in inflammatory bowel diseaseThe Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-AnalysisTherapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosisInduction of autoimmune disease by deletion of CTLA-4 in mice in adulthood.Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7Induced and natural regulatory T cells in the development of inflammatory bowel disease.Interferon-γ facilitates hepatic antiviral T cell retention for the maintenance of liver-induced systemic tolerance.The Interplay between the bone and the immune systemModulation of Phenotype and Function of Human CD4+CD25+ T Regulatory Lymphocytes Mediated by cAMP-Elevating AgentsThe Role of Inflammatory Cytokines, the RANKL/OPG Axis, and the Immunoskeletal Interface in Physiological Bone Turnover and Osteoporosis.Unmasking the immune recognition of prostate cancer with CTLA4 blockade.Multiple treg suppressive modules and their adaptability.Ipilimumab in prostate cancer.Treg and CTLA-4: two intertwining pathways to immune tolerance.
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Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 June 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation.
@en
Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation.
@nl
type
label
Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation.
@en
Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation.
@nl
prefLabel
Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation.
@en
Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation.
@nl
P356
P1433
P1476
Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation.
@en
P2093
Shimon Sakaguchi
P304
P356
10.1016/J.IT.2011.06.002
P577
2011-06-30T00:00:00Z