The death-fold superfamily of homotypic interaction motifs.
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The CLRX.1/NOD24 (NLRP2P) pseudogene codes a functional negative regulator of NF-κB, pyrin-only protein 4A comprehensive manually curated protein-protein interaction database for the Death Domain superfamilyPyrin- and CARD-only Proteins as Regulators of NLR FunctionsBiochemical and structural aspects of the ATP-binding domain in inflammasome-forming human NLRP proteinsStructural and Functional Analysis of the NLRP4 Pyrin DomainStructure of the Absent in Melanoma 2 (AIM2) Pyrin Domain Provides Insights into the Mechanisms of AIM2 Autoinhibition and Inflammasome AssemblyThe structure of the CARD8 caspase-recruitment domain suggests its association with the FIIND domain and procaspases through adjacent surfacesMechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulationThree-Dimensional Structure of Human NLRP10/PYNOD Pyrin Domain Reveals a Homotypic Interaction Site Distinct from Its Mouse HomologueStructure of the caspase-recruitment domain from a zebrafish guanylate-binding proteinStructures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signalingCrystal Structure of the F27G AIM2 PYD Mutant and Similarities of Its Self-Association to DED/DED InteractionsStructural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signallingStructural basis for the prion-like MAVS filaments in antiviral innate immunityThe structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidizedStructures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactionsInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseInhibiting the inflammasome: one domain at a timeIdentification of multifaceted binding modes for pyrin and ASC pyrin domains gives insights into pyrin inflammasome assembly.Interaction between NOD2 and CARD9 involves the NOD2 NACHT and the linker region between the NOD2 CARDs and NACHT domain.The tandem CARDs of NOD2: intramolecular interactions and recognition of RIP2.Structural mechanisms in NLR inflammasome signaling.An updated view on the structure and function of PYRIN domains.Interaction patches of procaspase-1 caspase recruitment domains (CARDs) are differently involved in procaspase-1 activation and receptor-interacting protein 2 (RIP2)-dependent nuclear factor κB signalingN-terminal and C-terminal domains of calmodulin mediate FADD and TRADD interactionArtificial Loading of ASC Specks with Cytosolic Antigens.Computational analysis predicts the Kaposi's sarcoma-associated herpesvirus tegument protein ORF63 to be alpha helical.The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain FilamentsMultiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein.Structural insights of homotypic interaction domains in the ligand-receptor signal transduction of tumor necrosis factor (TNF).AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.The characterization of sponge NLRs provides insight into the origin and evolution of this innate immune gene family in animals.Design of an expression system to enhance MBP-mediated crystallizationTrue grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity.Structures of pattern recognition receptors reveal molecular mechanisms of autoinhibition, ligand recognition and oligomerization.PYRIN domains and their interactions in the apoptosis and inflammation signaling pathway.Viral modulation of programmed necrosis.Shining light on cell death processes - a novel biosensor for necroptosis, a newly described cell death program.The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-κB signaling.Caspase-11: arming the guards against bacterial infection.
P2860
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P2860
The death-fold superfamily of homotypic interaction motifs.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
The death-fold superfamily of homotypic interaction motifs.
@en
The death-fold superfamily of homotypic interaction motifs.
@nl
type
label
The death-fold superfamily of homotypic interaction motifs.
@en
The death-fold superfamily of homotypic interaction motifs.
@nl
prefLabel
The death-fold superfamily of homotypic interaction motifs.
@en
The death-fold superfamily of homotypic interaction motifs.
@nl
P1476
The death-fold superfamily of homotypic interaction motifs.
@en
P2093
Jelle Verspurten
Kristof Kersse
P304
P356
10.1016/J.TIBS.2011.06.006
P577
2011-07-26T00:00:00Z