The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms.
about
Role of cytochrome P450 in drug interactionsCrystal structure of human cytochrome P450 2D6Application of genomics to toxicology researchClinically significant pharmacokinetic drug interactions with psychoactive drugs: antidepressants and antipsychotics and the cytochrome P450 system.Clinically significant pharmacokinetic drug interactions between antiepileptic drugs.Gender-related differences in pharmacokinetics and their clinical significance.Polymorphism in the metabolism of drugs, including antidepressant drugs: comments on phenotypingRegional and cellular expression of CYP2D6 in human brain: higher levels in alcoholics.LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P-450 monooxygenase.Inhibition of human cytochrome P450 2D6 (CYP2D6) by methadone.Molecular heterogeneity of the XbaI defined 44kb allele of the CYP2D locus within the Caucasian population.Metabolic activation of toxins: tissue-specific expression and metabolism in target organs.Multiple genetic alterations in human carcinogenesis.Molecular mechanisms of the microsomal mixed function oxidases and biological and pathological implicationsThe unique regulation of brain cytochrome P450 2 (CYP2) family enzymes by drugs and genetics.Pharmacogenetic screening of the gene deletion and duplications of CYP2D6.Impact of CYP2D6 polymorphism on tamoxifen therapy: where are we?Consequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA.In vitro methods for assessing human hepatic drug metabolism: their use in drug development.Regional and cellular distribution of CYP2D subfamily members in rat brain.
P2860
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P2860
The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms.
@en
The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms.
@nl
type
label
The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms.
@en
The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms.
@nl
prefLabel
The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms.
@en
The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms.
@nl
P2093
P1476
The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms.
@en
P2093
P304
P356
10.1016/0163-7258(90)90096-K
P577
1990-01-01T00:00:00Z