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The pharmacogenetics of antiplatelet agents: towards personalized therapy?

The pharmacogenetics of antiplatelet agents: towards personalized therapy?

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Platelet-reactivity tests identify patients at risk of secondary cardiovascular events: a systematic review and meta-analysis Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics.Single nucleotide polymorphism network: a combinatorial paradigm for risk prediction.Influence of Cyp2c19*2 Gene Variant on Therapeutic Response During Clopidogrel Treatment in Patients with Carotid Artery Stenosis.The evolution of antiplatelet therapy in the treatment of acute coronary syndromes: from aspirin to the present day.Identifying determinants of variability to tailor aspirin therapy.Pharmacogenetics of antiplatelets and anticoagulants: a report on clopidogrel, warfarin and dabigatran.Pharmacogenomics of oral antiplatelet drugs.Expert consensus document: World Heart Federation expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI.CYP2C19 polymorphism frequency in Russian patients in Central Russia and Siberia with acute coronary syndrome.Cardiovascular pharmacogenetics: a promise for genomically-guided therapy and personalized medicine.Evaluation of pharmacokinetic, pharmacodynamic, efficacy, and safety data of low-dose ticagrelor versus standard dose in East Asians: a systematic review.Clopidogrel bioactivation and risk of bleeding in patients cotreated with angiotensin-converting enzyme inhibitors after myocardial infarction: a proof-of-concept study.Emerging Role of Precision Medicine in Cardiovascular Disease.

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The pharmacogenetics of antiplatelet agents: towards personalized therapy?

http://www.wikidata.org/entity/Q37913976

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article científic

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article scientifique

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articol științific

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artigo científico

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artigo científico

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artikel ilmiah

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artikull shkencor

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artículo científico

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name

The pharmacogenetics of antiplatelet agents: towards personalized therapy?

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The pharmacogenetics of antiplatelet agents: towards personalized therapy?

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The pharmacogenetics of antiplatelet agents: towards personalized therapy?

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The pharmacogenetics of antiplatelet agents: towards personalized therapy?

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The pharmacogenetics of antiplatelet agents: towards personalized therapy?

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The pharmacogenetics of antiplatelet agents: towards personalized therapy?

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NRCARDIO.2011.111

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Nature Reviews Cardiology

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The pharmacogenetics of antiplatelet agents: towards personalized therapy?

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Richard C Becker

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Tariq Ahmad

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P2860

Resistance in vitro to low-dose aspirin is associated with platelet PlA1 (GP IIIa) polymorphism but not with C807T(GP Ia/IIa) and C-5T Kozak (GP Ibalpha) polymorphisms

Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance

PlA polymorphism and platelet reactivity following clopidogrel loading dose in patients undergoing coronary stent implantation

Profile and prevalence of aspirin resistance in patients with cardiovascular disease

Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation

Cyclooxygenase-1 haplotype modulates platelet response to aspirin

Aspirin and clopidogrel resistance: an emerging clinical entity

Genetic variation in cyclooxygenase 1: effects on response to aspirin

Genetic polymorphisms of the platelet receptors P2Y(12), P2Y(1) and GP IIIa and response to aspirin and clopidogrel

Contribution of gene sequence variations of the hepatic cytochrome P450 3A4 enzyme to variability in individual responsiveness to clopidogrel

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560-571

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scholarly article

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10.1038/NRCARDIO.2011.111

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2011-08-09T00:00:00Z

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21826075

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