Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine. - Wikidata - awgldk - TriplyDB

Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.

Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.

http://www.wikidata.org/entity/Q37922799

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The TRPA1 channel in migraine mechanism and treatment Calcitonin gene-related peptide: physiology and pathophysiology The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors Heat hyperalgesia and mechanical hypersensitivity induced by calcitonin gene-related peptide in a mouse model of neurofibromatosis.Role of peptidergic nerve terminals in the skin: reversal of thermal sensation by calcitonin gene-related peptide in TRPV1-depleted neuropathy.A second trigeminal CGRP receptor: function and expression of the AMY1 receptor.DNA methylation of RAMP1 gene in migraine: an exploratory analysis.Roles of CLR/RAMP receptor signaling in reproduction and development.CGRP in the trigeminovascular system: a role for CGRP, adrenomedullin and amylin receptors?Roles of proteolysis in regulation of GPCR function.Structure of Class B GPCRs: new horizons for drug discovery.CGRP antagonists and antibodies for the treatment of migraine.CGRP mechanism antagonists and migraine management.Chronic migraine treatment: from OnabotulinumtoxinA onwards.Amylin.Triptans and CGRP blockade - impact on the cranial vasculature.Secretin family (Class B) G protein-coupled receptors - from molecular to clinical perspectives.Update on the pharmacology of calcitonin/CGRP family of peptides: IUPHAR Review 25.Differential localization and characterization of functional calcitonin gene-related peptide receptors in human subcutaneous arteries.Calcitonin gene-related peptide receptor as a novel target for the management of people with episodic migraine: current evidence and safety profile of erenumab.CGRP receptor antagonist activity of olcegepant depends on the signalling pathway measured.CGRP and its receptors.The Influence of Inflammation and Nerve Damage on the Neurochemical Characterization of Calcitonin Gene-Related Peptide-Like Immunoreactive (CGRP-LI) Neurons in the Enteric Nervous System of the Porcine Descending Colon.The novel CGRP receptor antagonist BIBN4096BS alleviates a postoperative intestinal inflammation and prevents postoperative ileus.

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Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.

http://www.wikidata.org/entity/Q37922799

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artikel ilmiah

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Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.

@en

Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.

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type

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Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.

@en

Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.

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prefLabel

Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.

@en

Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.

@nl

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J.1476-5381.2011.01633.X

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British Journal of Pharmacology

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Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.

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Christopher A Salvatore

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Eric L Moore

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P2860

Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling

RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor

Novel function for receptor activity-modifying proteins (RAMPs) in post-endocytic receptor trafficking

Crystal structure of the human receptor activity-modifying protein 1 extracellular domain

Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism

Multiple amylin receptors arise from receptor activity-modifying protein interaction with the calcitonin receptor gene product

International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors

Immunohistochemical localization of calcitonin receptor-like receptor and receptor activity-modifying proteins in the human cerebral vasculature

Novel receptor partners and function of receptor activity-modifying proteins

CGRP may play a causative role in migraine

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66-78

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scholarly article

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10.1111/J.1476-5381.2011.01633.X

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1

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21871019

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migraine disorder

G protein-coupled receptor

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