The role of mitogen- and stress-activated protein kinase pathways in melanoma.
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NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivoDiscrepant alterations in main candidate genes among multiple primary melanomasComplex formation between S100B protein and the p90 ribosomal S6 kinase (RSK) in malignant melanoma is calcium-dependent and inhibits extracellular signal-regulated kinase (ERK)-mediated phosphorylation of RSKPDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation.Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo.Galangin induces B16F10 melanoma cell apoptosis via mitochondrial pathway and sustained activation of p38 MAPK.Therapeutic implications of targeting the PI3Kinase/AKT/mTOR signaling module in melanoma therapy.FRIZZLED7 Is Required for Tumor Inititation and Metastatic Growth of Melanoma Cells.Decursin from Angelica gigas Nakai Inhibits B16F10 Melanoma Growth Through Induction of Apoptosis.Downregulation of the Ubiquitin Ligase RNF125 Underlies Resistance of Melanoma Cells to BRAF Inhibitors via JAK1 Deregulation.MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis, and potentiates antineoplastic effect of cisplatin in ovarian cancer.Isoangustone A, a novel licorice compound, inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanomaHope and fear for interferon: the receptor-centric outlook on the future of interferon therapy.Melanoma metastasis: new concepts and evolving paradigms.Immunogenic, cellular, and angiogenic drivers of tumor dormancy--a melanoma view.Differential effects of p38 MAP kinase inhibitors SB203580 and SB202190 on growth and migration of human MDA-MB-231 cancer cell line.Optimal Use of BRAF Targeting Therapy in the Immunotherapy Era.Interleukin-6 drives melanoma cell motility through p38α-MAPK-dependent up-regulation of WNT5A expression.Sulforaphane-induced apoptosis involves p53 and p38 in melanoma cells.Role of c-Jun N-terminal kinase isoforms in the cellular activity of melanoma cell lines.Attenuation of neointimal formation with netrin-1 and netrin-1 preconditioned endothelial progenitor cells.GADD45α is involved in the apoptosis of lymphocytes induced by riboflavin and ultraviolet light.P21-activated kinase 1 (PAK1) as a therapeutic target in BRAF wild-type melanoma.The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway.A phosphatidylinositol 3-kinase-Pax3 axis regulates Brn-2 expression in melanoma.UVB represses melanocyte cell migration and acts through β-catenin.JNK-ERK signalling in melanoma: rewired or entangled?
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The role of mitogen- and stress-activated protein kinase pathways in melanoma.
description
article científic
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article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
The role of mitogen- and stress-activated protein kinase pathways in melanoma.
@en
The role of mitogen- and stress-activated protein kinase pathways in melanoma.
@nl
type
label
The role of mitogen- and stress-activated protein kinase pathways in melanoma.
@en
The role of mitogen- and stress-activated protein kinase pathways in melanoma.
@nl
prefLabel
The role of mitogen- and stress-activated protein kinase pathways in melanoma.
@en
The role of mitogen- and stress-activated protein kinase pathways in melanoma.
@nl
P2860
P1476
The role of mitogen- and stress-activated protein kinase pathways in melanoma.
@en
P2093
Pablo Lopez-Bergami
P2860
P304
P356
10.1111/J.1755-148X.2011.00908.X
P577
2011-10-01T00:00:00Z