AMPK and mTOR in cellular energy homeostasis and drug targets.
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Natural Products as Tools for Defining How Cellular Metabolism Influences Cellular Immune and Inflammatory Function during Chronic InfectionTargeting autophagy in cancer management - strategies and developmentsThe neurology of mTORThe dynamic nature of the kinomeFeeding uninvited guests: mTOR and AMPK set the table for intracellular pathogensRole of amino acid transporters in amino acid sensingAutophagy in malignant transformation and cancer progressionThe role of placental nutrient sensing in maternal-fetal resource allocationNutrient regulation of the mTOR complex 1 signaling pathwaySRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heartThe Complexity of Targeting PI3K-Akt-mTOR Signalling in Human Acute Myeloid Leukaemia: The Importance of Leukemic Cell Heterogeneity, Neighbouring Mesenchymal Stem Cells and Immunocompetent CellsCell biology. Metabolic control of cell deathIdentification of an annonaceous acetogenin mimetic, AA005, as an AMPK activator and autophagy inducer in colon cancer cellsSalinomycin activates AMP-activated protein kinase-dependent autophagy in cultured osteoblastoma cells: a negative regulator against cell apoptosisGAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathwaysMetformin Treatment Does Not Inhibit Growth of Pancreatic Cancer Patient-Derived XenograftsEnergy intake and exercise as determinants of brain health and vulnerability to injury and diseaseThe brain's response to an essential amino acid-deficient diet and the circuitous route to a better mealGaps in Aging Research as it Applies to Rheumatologic Clinical Care.Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance.Sleep deprivation impairs memory by attenuating mTORC1-dependent protein synthesis.Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy LifespanRecent progress in metabolic signaling pathways regulating aging and life spanCryptolepine inhibits melanoma cell growth through coordinated changes in mitochondrial biogenesis, dynamics and metabolic tumor suppressor AMPKα1/2-LKB1.Exercise-induced skeletal muscle remodeling and metabolic adaptation: redox signaling and role of autophagy.Somatic cells regulate maternal mRNA translation and developmental competence of mouse oocytesFast metabolic response to drug intervention through analysis on a miniaturized, highly integrated molecular imaging systemRegulation of yeast G protein signaling by the kinases that activate the AMPK homolog Snf1.Ras transformation uncouples the kinesin-coordinated cellular nutrient responseAkt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment.The importance of autophagy regulation in breast cancer development and treatment.Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat dietThe evolution of the TOR pathway and its role in cancer.A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrityIDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan.Mechanisms underlying the anti-aging and anti-tumor effects of lithocholic bile acidAutophagy and ageing: implications for age-related neurodegenerative diseases.Phenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid.Autophagy and cardiometabolic risk factors.
P2860
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P2860
AMPK and mTOR in cellular energy homeostasis and drug targets.
description
article científic
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article scientifique
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articol științific
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articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
AMPK and mTOR in cellular energy homeostasis and drug targets.
@en
AMPK and mTOR in cellular energy homeostasis and drug targets.
@nl
type
label
AMPK and mTOR in cellular energy homeostasis and drug targets.
@en
AMPK and mTOR in cellular energy homeostasis and drug targets.
@nl
prefLabel
AMPK and mTOR in cellular energy homeostasis and drug targets.
@en
AMPK and mTOR in cellular energy homeostasis and drug targets.
@nl
P2093
P1476
AMPK and mTOR in cellular energy homeostasis and drug targets.
@en
P2093
Joungmok Kim
Kun-Liang Guan
P304
P356
10.1146/ANNUREV-PHARMTOX-010611-134537
P577
2011-10-17T00:00:00Z