A unified hypothesis for the complex genetics of HLA associations with IDDM.
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Genetics of type 1 diabetes mellitusPD-1 deficiency reveals various tissue-specific autoimmunity by H-2b and dose-dependent requirement of H-2g7 for diabetes in NOD mice.Type 1 1/2 diabetes: myth or reality?Properties of HLA class II molecules divergently associated with Goodpasture's disease.Association of HLA class II genes with susceptibility to Crohn's disease.Differences in self-peptide binding between T1D-related susceptible and protective DR4 subtypes.Molecular properties of HLA-DQ alleles conferring susceptibility to or protection from insulin-dependent diabetes mellitus: keys to the fate of islet beta-cells.Human type 1 diabetes is associated with T cell autoimmunity to zinc transporter 8.HLA-DQ primarily confers protection and HLA-DR susceptibility in type I (insulin-dependent) diabetes studied in population-based affected families and controls.Cell-surface MHC density profiling reveals instability of autoimmunity-associated HLA.Role of HLA genes in predisposition to develop insulin-dependent diabetes mellitus.I-E+ nonobese diabetic mice develop insulitis and diabetes.Determinant capture as a possible mechanism of protection afforded by major histocompatibility complex class II molecules in autoimmune diseaseUse of recombinant congenic and congenic strains of NOD mice to identify a new insulin-dependent diabetes resistance geneResistance alleles at two non-major histocompatibility complex-linked insulin-dependent diabetes loci on chromosome 3, Idd3 and Idd10, protect nonobese diabetic mice from diabetesA major histocompatibility complex class II restriction for BioBreeding/Worcester diabetes-inducing T cells.Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities.Analysis of the role of variation of major histocompatibility complex class II expression on nonobese diabetic (NOD) peripheral T cell responseFailure of a protective major histocompatibility complex class II molecule to delete autoreactive T cells in autoimmune diabetes.Allele-specific DNA-protein interactions associated with the X-box regulatory region of the DQB1*0302 gene.Associations of human leukocyte antigens with autoimmune diseases: challenges in identifying the mechanism.Functional effects of a natural polymorphism in the transcriptional regulatory sequence of HLA-DQB1.Type I insulin-dependent diabetes mellitus: a model for autoimmune polygenic disorders.Reevaluation of the importance of polymorphic HLA class II alleles and amino acids in the susceptibility of individuals of different populations to type I diabetes.HLA class II DR-DQ amino acids and insulin-dependent diabetes mellitus: application of the haplotype method.Major histocompatibility complex-linked control of autoimmunity.Analysis of HLA haplotypes in families with type 1 diabetes mellitus in La Réunion island.Incidence, prevalence, and mortality of insulin-dependent (type 1) diabetes mellitus in Lithuanian children during 1983-98.Both central and peripheral tolerance mechanisms play roles in diabetes prevention in NOD-E transgenic mice.Como entender a associação entre o sistema HLA e as doenças auto-imunes endócrinas
P2860
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P2860
A unified hypothesis for the complex genetics of HLA associations with IDDM.
description
article científic
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article scientifique
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articol științific
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articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artículo científico
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A unified hypothesis for the complex genetics of HLA associations with IDDM.
@en
A unified hypothesis for the complex genetics of HLA associations with IDDM.
@nl
type
label
A unified hypothesis for the complex genetics of HLA associations with IDDM.
@en
A unified hypothesis for the complex genetics of HLA associations with IDDM.
@nl
prefLabel
A unified hypothesis for the complex genetics of HLA associations with IDDM.
@en
A unified hypothesis for the complex genetics of HLA associations with IDDM.
@nl
P356
P1433
P1476
A unified hypothesis for the complex genetics of HLA associations with IDDM.
@en
P2093
P304
P356
10.2337/DIAB.39.10.1153
P407
P577
1990-10-01T00:00:00Z