The GM-CSF receptor family: mechanism of activation and implications for disease. - Wikidata - awgldk - TriplyDB

The GM-CSF receptor family: mechanism of activation and implications for disease.

The GM-CSF receptor family: mechanism of activation and implications for disease.

http://www.wikidata.org/entity/Q37976887

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Bridge between neuroimmunity and traumatic brain injury A role for G-CSF and GM-CSF in nonmyeloid cancers Inflammatory cytokines: potential biomarkers of immunologic dysfunction in autism spectrum disorders CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts Endothelial cells expressing low levels of CD143 (ACE) exhibit enhanced sprouting and potency in relieving tissue ischemia.Localized interleukin-12 delivery for immunotherapy of solid tumours.The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling.The MAPK ERK5, but not ERK1/2, inhibits the progression of monocytic phenotype to the functioning macrophage.Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis.CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors Th2 cytokine antagonists: potential treatments for severe asthma.Granulocyte macrophage colony-stimulating factor and the intestinal innate immune cell homeostasis in Crohn's disease.CD 123 is a membrane biomarker and a therapeutic target in hematologic malignancies.Side effects of cytokines approved for therapy.Anti-inflammatory effect of 635 nm irradiations on in vitro direct/indirect irradiation model.CBL linker region and RING finger mutations lead to enhanced granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling via elevated levels of JAK2 and LYN.Granulocyte-macrophage colony-stimulating factor (GM-CSF) is released by female mouse bladder urothelial cells and expressed by the urothelium as an early response to lipopolysaccharides (LPS).Brief report: serpin Spi2A as a novel modulator of hematopoietic progenitor cell formation.Development of a rapid streptavidin capture-based assay for the tyrosine phosphorylated CSF-1R in peripheral blood mononuclear cells.Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GM-CSF-PD-L1 pathway.Expression and role of granulocyte macrophage colony-stimulating factor receptor (GM-CSFR) and granulocyte colony-stimulating factor receptor (G-CSFR) on Ph-positive acute B lymphoblastic leukemia.

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The GM-CSF receptor family: mechanism of activation and implications for disease.

http://www.wikidata.org/entity/Q37976887

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artikel ilmiah

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The GM-CSF receptor family: mechanism of activation and implications for disease.

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The GM-CSF receptor family: mechanism of activation and implications for disease.

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type

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The GM-CSF receptor family: mechanism of activation and implications for disease.

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The GM-CSF receptor family: mechanism of activation and implications for disease.

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The GM-CSF receptor family: mechanism of activation and implications for disease.

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The GM-CSF receptor family: mechanism of activation and implications for disease.

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08977194.2011.649919

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Growth Factors Journal

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The GM-CSF receptor family: mechanism of activation and implications for disease.

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Daniel Thomas

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Michele Grimbaldeston

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Michelle Perugini

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Richard J D'Andrea

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Sophie E Broughton

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Timothy Hughes

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P2860

CBAP interacts with the un-liganded common beta-subunit of the GM-CSF/IL-3/IL-5 receptor and induces apoptosis via mitochondrial dysfunction

Inhibition of β1 integrin and IL-3Rβ common subunit interaction hinders tumour angiogenesis

Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch

Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system

The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

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63-75

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scholarly article

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10.3109/08977194.2011.649919

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2

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30

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Stuart M Pitson

Michael W Parker

Hayley S. Ramshaw

Joanna M Woodcock

Timothy R Hercus

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2012-01-18T00:00:00Z

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221759147

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22257375

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