mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.

mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.

Item
http://www.wikidata.org/entity/Q37979160
Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumorsToward the use of precision medicine for the treatment of head and neck squamous cell carcinomamTOR co-targeting in cetuximab resistance in head and neck cancers harboring PIK3CA and RAS mutations.Enhanced genetic modification of adult growth factor mobilized peripheral blood hematopoietic stem and progenitor cells with rapamycin.Prevention of tumor growth driven by PIK3CA and HPV oncogenes by targeting mTOR signaling with metformin in oral squamous carcinomas expressing OCT3.Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells.A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancersThe CDK4/6 inhibitor LY2835219 has potent activity in combination with mTOR inhibitor in head and neck squamous cell carcinomamTOR inhibition as an adjuvant therapy in a metastatic model of HPV+ HNSCC.A positive feedback loop involving EGFR/Akt/mTORC1 and IKK/NF-kB regulates head and neck squamous cell carcinoma proliferation.Targeting cellular and molecular drivers of head and neck squamous cell carcinoma: current options and emerging perspectives.Temsirolimus and chloroquine cooperatively exhibit a potent antitumor effect against colorectal cancer cells.Dysregulations in the PI3K pathway and targeted therapies for head and neck squamous cell carcinomaDifferential expression of organic cation transporter OCT-3 in oral premalignant and malignant lesions: potential implications in the antineoplastic effects of metformin.Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.Cooperation Between Pten and Smad4 in Murine Salivary Gland Tumor Formation and Progression.mTOR, metabolism, and the immune response in HPV-positive head and neck squamous cell cancer
P2860

mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.

Item
http://www.wikidata.org/entity/Q37979160
description
article científic
@ca
article scientifique
@fr
articol științific
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articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
@id
artikull shkencor
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artículo científico
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name
mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.
@en
mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.
@nl
type
label
mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.
@en
mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.
@nl
prefLabel
mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.
@en
mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P698
P921
P356
P1433
P1476
mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P698
P921