Sigma-1 receptors: potential targets for the treatment of substance abuse.
about
The cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disordersGlial modulators as potential treatments of psychostimulant abuseSN79, a sigma receptor ligand, blocks methamphetamine-induced microglial activation and cytokine upregulationPotential Molecular Mechanisms on the Role of the Sigma-1 Receptor in the Action of Cocaine and MethamphetamineRelationship between cerebral sigma-1 receptor occupancy and attenuation of cocaine's motor stimulatory effects in mice by PD144418Ether modifications to 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine (SA4503): effects on binding affinity and selectivity for sigma receptors and monoamine transporters.Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaineRole of the Sigma-1 receptor in Amyotrophic Lateral Sclerosis (ALS)Sigma1 receptors inhibit store-operated Ca2+ entry by attenuating coupling of STIM1 to Orai1Tetrahydroprotoberberine alkaloids with dopamine and σ receptor affinity.Sigma receptors [σRs]: biology in normal and diseased statesPharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo.Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.Selective sigma-1 receptor antagonists for the treatment of pain.Pathological Overeating: Emerging Evidence for a Compulsivity Construct.Sigma-1 (σ1) Receptor in Memory and Neurodegenerative Diseases.Sigma Receptors and Substance Use Disorders.Sigma Receptor Binding Assays.Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction.Radiosynthesis and in vivo evaluation of a novel σ1 selective PET ligand.The σ1 receptor engages the redox-regulated HINT1 protein to bring opioid analgesia under NMDA receptor negative control.A selective sigma-2 receptor ligand antagonizes cocaine-induced hyperlocomotion in mice.Radiosynthesis and First-In-Human PET/MRI Evaluation with Clinical-Grade [18F]FTC-146.The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats.Fluorinated PET Tracers for Molecular Imaging of σ1 Receptors in the Central Nervous System.The Sigma-1 Receptor-A Therapeutic Target for the Treatment of ALS?Synthesis, radiolabelling, and evaluation of [11C]PB212 as a radioligand for imaging sigma-1 receptors using PET.The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases.Neuropharmacology of compulsive eating.Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor
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P2860
Sigma-1 receptors: potential targets for the treatment of substance abuse.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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Sigma-1 receptors: potential targets for the treatment of substance abuse.
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Sigma-1 receptors: potential targets for the treatment of substance abuse.
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Sigma-1 receptors: potential targets for the treatment of substance abuse.
@en
Sigma-1 receptors: potential targets for the treatment of substance abuse.
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Sigma-1 receptors: potential targets for the treatment of substance abuse.
@en
Sigma-1 receptors: potential targets for the treatment of substance abuse.
@nl
P2093
P1476
Sigma-1 receptors: potential targets for the treatment of substance abuse.
@en
P2093
Bahar Noorbakhsh
Matthew J Robson
Michael J Seminerio
Rae R Matsumoto
P304
P356
10.2174/138161212799436601
P577
2012-01-01T00:00:00Z