Exploiting bacterial iron acquisition: siderophore conjugates. - Wikidata - awgldk - TriplyDB

Exploiting bacterial iron acquisition: siderophore conjugates.

Exploiting bacterial iron acquisition: siderophore conjugates.

http://www.wikidata.org/entity/Q37990947

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Targeting virulence: salmochelin modification tunes the antibacterial activity spectrum of β-lactams for pathogen-selective killing of Escherichia coli.Beyond iron: non-classical biological functions of bacterial siderophores Evaluation of Gallium Citrate Formulations against a Multidrug-Resistant Strain of Klebsiella pneumoniae in a Murine Wound Model of Infection.Iron transport-mediated drug delivery: practical syntheses and in vitro antibacterial studies of tris-catecholate siderophore-aminopenicillin conjugates reveals selectively potent antipseudomonal activity New Structural Templates for Clinically Validated and Novel Targets in Antimicrobial Drug Research and Development.Targeting iron assimilation to develop new antibacterials.Preparation of bifunctional isocyanate hydroxamate linkers: Synthesis of carbamate and urea tethered polyhydroxamic acid chelators.Syntheses of Siderophore-Drug Conjugates Using a Convergent Thiol-Maleimide System Trihydroxamate siderophore-fluoroquinolone conjugates are selective sideromycin antibiotics that target Staphylococcus aureus.Biscatecholate-monohydroxamate mixed ligand siderophore-carbacephalosporin conjugates are selective sideromycin antibiotics that target Acinetobacter baumannii Insights on how the Mycobacterium tuberculosis heme uptake pathway can be used as a drug target.Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa.Siderophore-based immunization strategy to inhibit growth of enteric pathogens.Siderophores for molecular imaging applications.Siderophore-based detection of Fe(III) and microbial pathogens.Combating multidrug-resistant bacteria: current strategies for the discovery of novel antibacterials.Siderophore production by actinobacteria.Optimization of the biotechnological production of a novel class of anti-MRSA antibiotics from Chitinophaga sancti.Mass spectrometry-derived systems biology technologies delineate the system's biochemical applications of siderophores.Multivalent Siderophore-DOTAM Conjugates as Theranostics for Imaging and Treatment of Bacterial Infections.Bifunctional antimicrobial conjugates and hybrid antimicrobials.Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii.Catechol siderophores repress the pyochelin pathway and activate the enterobactin pathway in Pseudomonas aeruginosa: an opportunity for siderophore-antibiotic conjugates development.Enterobactin-mediated delivery of β-lactam antibiotics enhances antibacterial activity against pathogenic Escherichia coli.Siderophore production by pathogenic mucorales and uptake of deferoxamine B.Biomimetic ferrichrome: structural motifs for switching between narrow- and broad-spectrum activities in P. putida and E. coli.Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase.Determination of the Molecular Structures of Ferric Enterobactin and Ferric Enantioenterobactin Using Racemic Crystallography.Antibacterial and β-Lactamase Inhibitory Activity of Monocyclic β-Lactams.Utilizing an iron(iii)-chelation masking strategy to prepare mono- and bis-functionalized aerobactin analogues for targeting pathogenic bacteria.Siderophore-fluoroquinolone conjugates containing potential reduction-triggered linkers for drug release: synthesis and antibacterial activity.Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin-Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity.Development of a novel fluorescence probe capable of assessing the cytoplasmic entry of siderophore-based conjugates.

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P2860

Exploiting bacterial iron acquisition: siderophore conjugates.

http://www.wikidata.org/entity/Q37990947

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article científic

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Exploiting bacterial iron acquisition: siderophore conjugates.

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Exploiting bacterial iron acquisition: siderophore conjugates.

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Exploiting bacterial iron acquisition: siderophore conjugates.

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Exploiting bacterial iron acquisition: siderophore conjugates.

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Exploiting bacterial iron acquisition: siderophore conjugates.

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Exploiting bacterial iron acquisition: siderophore conjugates.

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Future Medicinal Chemistry

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Exploiting bacterial iron acquisition: siderophore conjugates

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Cheng Ji

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Marvin J Miller

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Raúl E Juárez-Hernández

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P2860

Siderophore-based iron acquisition and pathogen control

The transition metal gallium disrupts Pseudomonas aeruginosa iron metabolism and has antimicrobial and antibiofilm activity

Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa

Synthesis and biological evaluation of a pyoverdin-beta-lactam conjugate: a new type of arginine-specific cross-linking in aqueous solution.

The discovery and development of modified penicillin- and cephalosporin-derived beta-lactamase inhibitors.

Total synthesis of the siderophore danoxamine.

Microcins, gene-encoded antibacterial peptides from enterobacteria.

Selective capture and identification of pathogenic bacteria using an immobilized siderophore.

Studies and syntheses of siderophores, microbial iron chelators, and analogs as potential drug delivery agents.

Chemistry and biology of siderophores.

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297-313

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scholarly article

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10.4155/FMC.11.191

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3

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2012-03-01T00:00:00Z

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22393938

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6901097

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