Amyotrophic lateral sclerosis: new insights into underlying molecular mechanisms and opportunities for therapeutic intervention.
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ALS Patient Stem Cells for Unveiling Disease Signatures of Motoneuron Susceptibility: Perspectives on the Deadly Mitochondria, ER Stress and Calcium TriadOxidative stress and mitochondrial damage: importance in non-SOD1 ALSRedox regulation in amyotrophic lateral sclerosisNeural transcriptome reveals molecular mechanisms for temporal control of vocalization across multiple timescalesRac1 at the crossroad of actin dynamics and neuroinflammation in Amyotrophic Lateral Sclerosis.Concise review: Stem cell therapies for amyotrophic lateral sclerosis: recent advances and prospects for the futureReactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signalingTissue-specific deregulation of selected HDACs characterizes ALS progression in mouse models: pharmacological characterization of SIRT1 and SIRT2 pathways.The P66Shc/mitochondrial permeability transition pore pathway determines neurodegeneration.SOD1 and DJ-1 converge at Nrf2 pathway: a clue for antioxidant therapeutic potential in neurodegenerationAstrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress.FUsed in sarcoma is a novel regulator of manganese superoxide dismutase gene transcription.Moving forward in clinical trials for ALS: motor neurons lead the way please.SIRT1 in neurodevelopment and brain senescence.Mitochondrial dynamism and the pathogenesis of Amyotrophic Lateral Sclerosis.Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration.Old versus New Mechanisms in the Pathogenesis of ALS.Inhibition of retrograde transport modulates misfolded protein accumulation and clearance in motoneuron diseases.Polyanion binding accelerates the formation of stable and low-toxic aggregates of ALS-linked SOD1 mutant A4V.Determining the Roles of Inositol Trisphosphate Receptors in Neurodegeneration: Interdisciplinary Perspectives on a Complex Topic.P2X7 Receptor Activation Modulates Autophagy in SOD1-G93A Mouse Microglia.Stress-Induced CDK5 Activation Disrupts Axonal Transport via Lis1/Ndel1/Dynein.Pur-alpha functionally interacts with FUS carrying ALS-associated mutations.The Emerging Role of the Major Histocompatibility Complex Class I in Amyotrophic Lateral Sclerosis.Synaptic Failure: Focus in an Integrative View of ALS.Real-time visualization of oxidative stress-mediated neurodegeneration of individual spinal motor neurons in vivo
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Amyotrophic lateral sclerosis: new insights into underlying molecular mechanisms and opportunities for therapeutic intervention.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Amyotrophic lateral sclerosis: ...... for therapeutic intervention.
@en
Amyotrophic lateral sclerosis: ...... for therapeutic intervention.
@nl
type
label
Amyotrophic lateral sclerosis: ...... for therapeutic intervention.
@en
Amyotrophic lateral sclerosis: ...... for therapeutic intervention.
@nl
prefLabel
Amyotrophic lateral sclerosis: ...... for therapeutic intervention.
@en
Amyotrophic lateral sclerosis: ...... for therapeutic intervention.
@nl
P50
P356
P1476
Amyotrophic lateral sclerosis: ...... s for therapeutic intervention
@en
P2093
Maria Grazia Pesaresi
Valeria Gerbino
P304
P356
10.1089/ARS.2011.4328
P577
2012-04-30T00:00:00Z