Medicinal chemistry based approaches and nanotechnology-based systems to improve CNS drug targeting and delivery.
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A Role for Fragment-Based Drug Design in Developing Novel Lead Compounds for Central Nervous System TargetsGetting into the brain: liposome-based strategies for effective drug delivery across the blood-brain barrierDiscovery and in vivo evaluation of novel RGD-modified lipid-polymer hybrid nanoparticles for targeted drug deliveryStrategies to improve delivery of anticancer drugs across the blood-brain barrier to treat glioblastoma.Potential Pathways for CNS Drug Delivery Across the Blood-Cerebrospinal Fluid BarrierNovel central nervous system drug delivery systems.A Cyclic Peptide Mimic of the β-Amyloid Binding Domain on Transthyretin.In vivo theranostics at the peri-infarct region in cerebral ischemia.Tissue inhibitor of matrix metalloproteinases-1 loaded poly(lactic-co-glycolic acid) nanoparticles for delivery across the blood-brain barrier.Liposomes and nanotechnology in drug development: focus on neurological targets.Strategies to target drugs to gliomas and CNS metastases of solid tumors.Nanoparticulate strategies for the treatment of polyglutamine diseases by halting the protein aggregation process.Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal graftingNovel functionalization strategies of polymeric nanoparticles as carriers for brain medications.Transport across the choroid plexus epithelium.N-(Pivaloyloxy)alkoxy-carbonyl Prodrugs of the Glutamine Antagonist 6-Diazo-5-oxo-l-norleucine (DON) as a Potential Treatment for HIV Associated Neurocognitive Disorders.Direct, long-term intrathecal application of therapeutics to the rodent CNS.Use of PEGylated Immunoliposomes to Deliver Dopamine Across the Blood-Brain Barrier in a Rat Model of Parkinson's Disease.Identification and characterization of highly versatile peptide-vectors that bind non-competitively to the low-density lipoprotein receptor for in vivo targeting and delivery of small molecules and protein cargos.
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P2860
Medicinal chemistry based approaches and nanotechnology-based systems to improve CNS drug targeting and delivery.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Medicinal chemistry based appr ...... S drug targeting and delivery.
@en
Medicinal chemistry based appr ...... S drug targeting and delivery.
@nl
type
label
Medicinal chemistry based appr ...... S drug targeting and delivery.
@en
Medicinal chemistry based appr ...... S drug targeting and delivery.
@nl
prefLabel
Medicinal chemistry based appr ...... S drug targeting and delivery.
@en
Medicinal chemistry based appr ...... S drug targeting and delivery.
@nl
P2860
P356
P1476
Medicinal chemistry based appr ...... S drug targeting and delivery.
@en
P2093
Michel Khrestchatisky
Patrick Vlieghe
P2860
P304
P356
10.1002/MED.21252
P577
2012-03-20T00:00:00Z