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Lost in Translation (LiT): IUPHAR Review 6An update on antibody-based immunotherapies for Clostridium difficile infectionBispecific antibodies and their applicationsSpecific in vivo knockdown of protein function by intrabodiesImmunotherapeutic organoids: a new approach to cancer treatmentNovel immunotherapies for hematologic malignanciesDual anti-idiotypic purification of a novel, native-format biparatopic anti-MET antibody with improved in vitro and in vivo efficacy.Crystal Structure of an Anti-Ang2 CrossFab Demonstrates Complete Structural and Functional Integrity of the Variable DomainImproving biophysical properties of a bispecific antibody scaffold to aid developabilityImmunoglobulin Fc Heterodimer Platform Technology: From Design to Applications in Therapeutic Antibodies and ProteinsIdentification and multidimensional optimization of an asymmetric bispecific IgG antibody mimicking the function of factor VIII cofactor activityCODV-Ig, a universal bispecific tetravalent and multifunctional immunoglobulin format for medical applications.Combating non-Hodgkin lymphoma by targeting both CD20 and HLA-DR through CD20-243 CrossMabSimultaneous targeting of CD44 and EpCAM with a bispecific aptamer effectively inhibits intraperitoneal ovarian cancer growth.The development of bispecific antibodies and their applications in tumor immune escape.Design and applications of bispecific heterodimers: molecular imaging and beyondRetargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology "UniCAR".Discovery of hapten-specific scFv from a phage display library and applications for HER2-positive tumor imagingIn vitro and in vivo application of anti-cotinine antibody and cotinine-conjugated compounds.A FcγRIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy.O-glycosylation of glycine-serine linkers in recombinant Fc-fusion proteins: attachment of glycosaminoglycans and other intermediates with phosphorylation at the xylose sugar subunit.Tetraspecific ligand for tumor-targeted delivery of nanomaterials.Frontier of therapeutic antibody discovery: The challenges and how to face them.Lysibodies are IgG Fc fusions with lysin binding domains targeting Staphylococcus aureus wall carbohydrates for effective phagocytosis.Bispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activityNotch signaling regulates antigen sensitivity of naive CD4+ T cells by tuning co-stimulation.Therapeutic antibody engineering by high efficiency cell screening.A two-in-one antibody engineered from a humanized interleukin 4 antibody through mutation in heavy chain complementarity-determining regions.Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG.Retargeting T cells to GD2 pentasaccharide on human tumors using Bispecific humanized antibody.Identification of anti-ErbB2 dual variable domain immunoglobulin (DVD-Ig™) proteins with unique activities.A novel antibody engineering strategy for making monovalent bispecific heterodimeric IgG antibodies by electrostatic steering mechanism.Advanced mass spectrometry workflows for analyzing disulfide bonds in biologics.The Shark Strikes Twice: Hypervariable Loop 2 of Shark IgNAR Antibody Variable Domains and Its Potential to Function as an Autonomous Paratope.Engineering of Immunoglobulin Fc Heterodimers Using Yeast Surface-Displayed Combinatorial Fc Library ScreeningA Dual Target-directed Agent against Interleukin-6 Receptor and Tumor Necrosis Factor α ameliorates experimental arthritis.A Murine, Bispecific Monoclonal Antibody Simultaneously Recognizing β-Glucan and MP65 Determinants in Candida Species.'In-Format' screening of a novel bispecific antibody format reveals significant potency improvements relative to unformatted molecules.Noninvasive brain cancer imaging with a bispecific antibody fragment, generated via click chemistry.Nanocell targeting using engineered bispecific antibodies.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Dual targeting strategies with bispecific antibodies.
@en
Dual targeting strategies with bispecific antibodies.
@nl
type
label
Dual targeting strategies with bispecific antibodies.
@en
Dual targeting strategies with bispecific antibodies.
@nl
prefLabel
Dual targeting strategies with bispecific antibodies.
@en
Dual targeting strategies with bispecific antibodies.
@nl
P2860
P356
P1476
Dual targeting strategies with bispecific antibodies.
@en
P2093
Roland E Kontermann
P2860
P304
P356
10.4161/MABS.4.2.19000
P577
2012-03-01T00:00:00Z