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The Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated ProteinsProline-rich tyrosine kinase 2 (Pyk2) regulates IGF-I-induced cell motility and invasion of urothelial carcinoma cells.Polycyclic aromatic hydrocarbons-induced ROS accumulation enhances mutagenic potential of T-antigen from human polyomavirus JCGlargine safety, diabetes and cancer.Altered gene expression patterns during the initiation and promotion stages of neonatally diethylstilbestrol-induced hyperplasia/dysplasia/neoplasia in the hamster uterus.Genome-wide DNA methylation analysis reveals a potential mechanism for the pathogenesis and development of uterine leiomyomas.IRS1 gene polymorphisms Gly972Arg and Ala513Pro are not associated with insulin resistance and type 2 diabetes risk in non-obese Turkish populationDown-regulation of miR-126 is associated with colorectal cancer cells proliferation, migration and invasion by targeting IRS-1 via the AKT and ERK1/2 signaling pathwaysInsulin and IGF1 signalling pathways in human astrocytes in vitro and in vivo; characterisation, subcellular localisation and modulation of the receptors.Insulin therapy and cancer in type 2 diabetes.Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins.Flaxseed and its components differentially affect estrogen targets in pre-neoplastic hen ovariesMicroRNA-494 inhibits proliferation and metastasis of osteosarcoma through repressing insulin receptor substrate-1.IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivationmiR-144 suppresses the growth and metastasis of laryngeal squamous cell carcinoma by targeting IRS1.Transcriptome sequencing identifies ETV6-NTRK3 as a gene fusion involved in GIST.Synergistic drug combinations from electronic health records and gene expression.Review on the role of the human Polyomavirus JC in the development of tumors.miR-370 modulates insulin receptor substrate-1 expression and inhibits the tumor phenotypes of oral carcinoma.Anthropometric, metabolic and molecular determinants of human epidermal growth factor receptor 2 expression in luminal B breast cancer.miR-487b-3p Suppresses the Proliferation and Differentiation of Myoblasts by Targeting IRS1 in Skeletal Muscle Myogenesis.In vivo genome-wide binding interactions of mouse and human constitutive androstane receptors reveal novel gene targets
P2860
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P2860
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Nuclear IRS-1 and cancer
@en
Nuclear IRS-1 and cancer.
@nl
type
label
Nuclear IRS-1 and cancer
@en
Nuclear IRS-1 and cancer.
@nl
prefLabel
Nuclear IRS-1 and cancer
@en
Nuclear IRS-1 and cancer.
@nl
P2093
P2860
P356
P1476
Nuclear IRS-1 and cancer
@en
P2093
Adam Lassak
Joanna Trojanek
Krzysztof Reiss
Luis Del Valle
P2860
P304
P356
10.1002/JCP.24019
P577
2012-08-01T00:00:00Z