Malignant glioma: lessons from genomics, mouse models, and stem cells.
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Novel anti-glioblastoma agents and therapeutic combinations identified from a collection of FDA approved drugsEpigenetic pathways and glioblastoma treatmentROS and Brain Gliomas: An Overview of Potential and Innovative Therapeutic StrategiesBrain tumor modeling using the CRISPR/Cas9 system: state of the art and view to the futureRASopathies: unraveling mechanisms with animal modelsIn vivo models of brain tumors: roles of genetically engineered mouse models in understanding tumor biology and use in preclinical studiesCancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistanceIt takes two to tango, a dance between the cells of origin and cancer stem cells in the Drosophila larval brainHeterogeneity of epidermal growth factor receptor signalling networks in glioblastomaContemporary murine models in preclinical astrocytoma drug developmentRadiation therapy-induced tumor invasiveness is associated with SDF-1-regulated macrophage mobilization and vasculogenesisNeuroblastoma tyrosine kinase signaling networks involve FYN and LYN in endosomes and lipid raftsAsymmetric cell division of stem and progenitor cells during homeostasis and cancerSerum-Induced Differentiation of Glioblastoma Neurospheres Leads to Enhanced Migration/Invasion Capacity That Is Associated with Increased MMP9Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastomaA restricted cell population propagates glioblastoma growth after chemotherapyTranscription factors FOXG1 and Groucho/TLE promote glioblastoma growthQki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation.HMMR maintains the stemness and tumorigenicity of glioblastoma stem-like cells.Epigenetic regulation by chromatin activation mark H3K4me3 in primate progenitor cells within adult neurogenic nicheLipid vesicles containing transferrin receptor binding peptide TfR-T12 and octa-arginine conjugate stearyl-R8 efficiently treat brain glioma along with glioma stem cellsZnf179 induces differentiation and growth arrest of human primary glioblastoma multiforme in a p53-dependent cell cycle pathway.Lentiviral-induced high-grade gliomas in rats: the effects of PDGFB, HRAS-G12V, AKT, and IDH1-R132H.The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway.Brevican knockdown reduces late-stage glioma tumor aggressiveness.Neurofibromatosis type 1: modeling CNS dysfunction.Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma.Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma.Transcriptional analysis of aggressiveness and heterogeneity across grades of astrocytomas.Micro-environment causes reversible changes in DNA methylation and mRNA expression profiles in patient-derived glioma stem cellsRasGRP3 regulates the migration of glioma cells via interaction with Arp3Antitumor activity of a polypyridyl chelating ligand: in vitro and in vivo inhibition of glioma.A unique four-hub protein cluster associates to glioblastoma progression.The role of metabolic therapy in treating glioblastoma multiforme.In vitro screen of a small molecule inhibitor drug library identifies multiple compounds that synergize with oncolytic myxoma virus against human brain tumor-initiating cellsNuclear-encoded cytochrome c oxidase subunit 4 regulates BMI1 expression and determines proliferative capacity of high-grade gliomasRadiosensitization of Primary Human Glioblastoma Stem-like Cells with Low-Dose AKT Inhibition.Reduction in gap junction intercellular communication promotes glioma migration.3-Bromopyruvate inhibits cell proliferation and induces apoptosis in CD133+ population in human glioma.Associations between SOX2 and miR-200b expression with the clinicopathological characteristics and prognosis of patients with glioma.
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P2860
Malignant glioma: lessons from genomics, mouse models, and stem cells.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Malignant glioma: lessons from genomics, mouse models, and stem cells.
@en
Malignant glioma: lessons from genomics, mouse models, and stem cells.
@nl
type
label
Malignant glioma: lessons from genomics, mouse models, and stem cells.
@en
Malignant glioma: lessons from genomics, mouse models, and stem cells.
@nl
prefLabel
Malignant glioma: lessons from genomics, mouse models, and stem cells.
@en
Malignant glioma: lessons from genomics, mouse models, and stem cells.
@nl
P2093
P2860
P1433
P1476
Malignant glioma: lessons from genomics, mouse models, and stem cells.
@en
P2093
Luis F Parada
Renée M McKay
P2860
P356
10.1016/J.CELL.2012.03.009
P407
P577
2012-03-01T00:00:00Z